Relations of plasma TG and HDL-C concentrations to body composition and plasma insulin levels are altered in men with small LDL particles.
Relations of plasma TG and HDL-C concentrations to body composition and plasma insulin levels are altered in men with small LDL particles.
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DOI:
10.1161/01.atv.14.7.1121
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发表时间:
1994-07
期刊:
影响因子:
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通讯作者:
L. Katzel;Ronald M. Krauss;Andrew P. Goldberg
中科院分区:
文献类型:
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作者:
L. Katzel;Ronald M. Krauss;Andrew P. Goldberg
Low-density lipoprotein (LDL) subclass pattern B is characterized by a predominance of small, dense LDL particles (LDL peak particle size 255 A, LDL pattern A). Men with LDL pattern B also had higher TG (1.76 +/- 0.60 versus 1.03 +/- 0.41 mmol/L, P < .0001) and lower HDL cholesterol (0.83 +/- 0.13 versus 1.06 +/- 0.29 mmol/L, P < .0001) and percent HDL2 subspecies (by gradient gel electrophoresis) (31 +/- 4 versus 43 +/- 6, P < .0001) levels than men with LDL pattern A, but the total cholesterol and LDL cholesterol levels did not differ between groups. Fasting glucose and insulin levels also did not differ between groups, but plasma glucose and insulin levels measured at 90 and 120 minutes during an oral glucose tolerance test were significantly higher in men with LDL pattern B.(ABSTRACT TRUNCATED AT 250 WORDS)