Preoperative Assessment of Extrathyroidal Extension of Papillary Thyroid Carcinoma Comparison of 2- and 3-Dimensional Sonography
Preoperative Assessment of Extrathyroidal Extension of Papillary Thyroid Carcinoma Comparison of 2- and 3-Dimensional Sonography
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DOI：
10.7863/ultra.33.5.819
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发表时间：
2014-05-01
影响因子：
2.3
通讯作者：
Park, Cheong Soo
中科院分区：
文献类型：
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作者：
Gweon, Hye Mi;Son, Eun Ju;Park, Cheong Soo
Objectives-本研究的目的是评估二维（2D）和三维（3D）超声检查的诊断性能和观察者之间的协议，用于评估甲状腺乳头状癌的甲状腺外延伸。Methods-共79例甲状腺乳头状癌患者进行了2D和3D超声检查的甲状腺乳头状癌术前分期包括在内。当二维超声显示病变与甲状腺包膜相邻时，进行三维超声检查。三名放射科医生审查了3个数据集：2D超声检查，3D超声检查，以及两者的组合集，用于肿瘤分期。分析甲状腺外侵犯的诊断性能，包括敏感性、特异性、阳性预测值、阴性预测值和准确性。3个放射科医师的观察者间的一致性进行了评估与kappa values.Results-The整体准确率为2D超声，3D超声，并结合预测甲状腺外的扩展分别为60.8%，66.2%和67.9%。联合组的准确性显著高于二维超声（P = 0.016）。3位评价者的观察者间一致性在2D超声检查中为中等（kappa = 0.33），在3D超声检查中为中等（kappa = 0.46），在2D超声检查中增加3D超声检查可以提高预测甲状腺乳头状癌向甲状腺外扩散的准确性和观察者间一致性。
Objectives-The purpose of this study was to evaluate the diagnostic performance and interobserver agreement of 2-dimensional (2D) and 3-dimensional (3D) sonography for evaluating extrathyroidal extension of papillary thyroid carcinoma.Methods-A total of 79 papillary thyroid carcinomas in 79 patients who underwent both 2D and 3D sonography for preoperative staging of papillary thyroid carcinoma were included. When the lesion was abutting on the thyroid capsule on 2D sonography, 3D sonography was performed. Three radiologists reviewed 3 data sets: 2D sonography, 3D sonography, and a combined set of both for tumor staging. The diagnostic performance, including sensitivity, specificity, positive predictive value, negative predictive value, and accuracy, for extrathyroidal extension was analyzed. Interobserver agreement of the 3 radiologists was assessed with kappa values.Results-The overall accuracy rates for 2D sonography, 3D sonography, and the combined set in predicting extrathyroidal extension were 60.8%, 66.2%, and 67.9%, respectively. The accuracy of the combined set was significantly higher than that of 2D sonography (P = .016). The interobserver agreement of the 3 reviewers was fair (kappa = 0.33) for 2D sonography and moderate for 3D sonography (kappa = 0.46) and the combined set (kappa = 0.49).Conclusions-Adding 3D sonography to 2D sonography could improve the accuracy and interobserver agreement for predicting extrathyroidal extension of papillary thyroid carcinoma.