Impaired functioning and quality of life in severe migraine: the role of catastrophizing and associated symptoms
Impaired functioning and quality of life in severe migraine: the role of catastrophizing and associated symptoms
复制标题
DOI：
10.1111/j.1468-2982.2007.01420.x
复制
发表时间：
2007-10-01
期刊：
影响因子：
4.9
通讯作者：
Heh, V.
中科院分区：
文献类型：
--
作者：
Holroyd, K. A.;Drew, J. B.;Heh, V.
偏头痛特征与功能和生活质量 (Fn/QoL) 受损有关，但其他因素对头痛患者 Fn/QoL 的影响很大程度上尚未被探索。我们检查了与 Fn/QoL 相关的灾难性共病焦虑/抑郁和偏头痛特征，并探讨了五种 Fn/QoL 指标之间这些关系的一致性。我们对 232 名频繁偏头痛患者进行了共病精神诊断评估，他们完成了焦虑、抑郁和灾难化测量，在日记中记录了偏头痛特征，并完成了五项 Fn/QoL 测量（四项自我报告问卷、一项日记残疾测量）。向后回归显示相关症状（畏光、恐声、恶心）的灾难性和严重程度独立预测了所有五项指标的 Fn/QoL（β 权重 0.16-0.50，所有 P < 0.01）。这是首次证明偏头痛的心理反应（灾难化）与 Fn/QoL 受损相关，与偏头痛特征和其他人口和心理变量无关。相关症状的严重程度也成为 Fn/QoL 的重要影响因素。
Migraine characteristics are associated with impaired functioning and quality of life (Fn/QoL), but the impact of other factors on Fn/QoL in headache patients is largely unexplored. We examined catastrophizing, comorbid anxiety/depression and migraine characteristics as related to Fn/QoL, and explored the consistency of these relationships across five Fn/QoL measures. We evaluated 232 frequent migraine sufferers for comorbid psychiatric diagnosis, and they completed anxiety, depression and catastrophizing measures, recorded migraine characteristics in a diary and completed five Fn/QoL measures (four self-report questionnaires, one diary disability measure). Backward regression revealed catastrophizing and severity of associated symptoms (photophobia, phonophobia, nausea) independently predicted Fn/QoL across all five measures (beta weights 0.16-0.50, all P < 0.01). This is the first demonstration that a psychological response to migraines (catastrophizing) is associated with impaired Fn/QoL independent of migraine characteristics and other demographic and psychological variables. Severity of associated symptoms also emerged as an important contributor to Fn/QoL.