The Effect of Carotid Occlusion in Cognition before Endarterectomy
The Effect of Carotid Occlusion in Cognition before Endarterectomy
复制标题
DOI：
10.1093/arclin/acs075
复制
发表时间：
2012-12-01
影响因子：
2.6
通讯作者：
Aguilar, Miquel
中科院分区：
文献类型：
--
作者：
Casas-Hernanz, Laura;Garolera, Maite;Aguilar, Miquel
颈动脉狭窄对认知的作用仍有待确定。为了研究颈动脉狭窄患者是否会增加认知障碍，我们研究了53名中度或重度颈动脉狭窄患者（无中风或痴呆症状）和53名对照组。我们描述了患者的哪些认知功能受损，以及是否根据侧边、狭窄的严重程度或神经症状的存在而存在差异。应用可重复电池神经心理状态评估，我们发现颈动脉狭窄患者在注意力、言语记忆、视觉空间容量和言语流畅性方面的认知表现较差。狭窄程度较轻的患者在学习和记忆方面得分高于健康对照患者。本研究结果提示，颈动脉严重狭窄患者的认知状态低于健康对照患者，这与颈动脉总狭窄程度有关。
The role of carotid stenosis on cognition remains to be determined. To study whether people with stenosis of the carotid artery have increased cognitive impairments, we studied 53 patients with moderate or severe carotid stenosis (with no symptoms of stroke or dementia) and 53 controls. We describe which cognitive functions were impaired in the patients and whether there were differences based on the side, the severity of the stenosis or the presence of neurological symptoms. Using the Repeatable Battery for the Assessment of Neuropsychological Status, we found that the patients with carotid stenosis had lower cognitive performances in attention, verbal memory, visuospatial capacity and verbal fluency. Patients with lesser degrees of stenosis than healthy control patients had better scores in learning and memory. The results from this study suggest that patients with severe carotid stenosis have a lower cognitive status than healthy control patients, which is associated with the degree of total carotid stenosis.