Prevalence of Atopic Dermatitis in Chinese Children aged 1-7 ys.
Prevalence of Atopic Dermatitis in Chinese Children aged 1-7 ys.
复制标题
中国1-7岁儿童特应性皮炎患病率。
DOI：
10.1038/srep29751
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发表时间：
2016-07-19
影响因子：
4.6
通讯作者：
Yao Z
中科院分区：
文献类型：
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作者：
Guo Y;Li P;Tang J;Han X;Zou X;Xu G;Xu Z;Wei F;Liu Q;Wang M;Xiao F;Zong W;Shen C;Li J;Liu J;Luo Y;Chang J;Sheng N;Dong C;Zhang D;Dai X;Zhou J;Meng C;Niu H;Shi X;Zhang X;Xiang J;Xu H;Ran Q;Zhou Y;Li M;Zhang H;Cheng R;Gao X;Wang H;Gu H;Ma L;Yao Z
特应性皮炎（AD）的患病率在世界范围内呈上升趋势。到目前为止，中国还没有面对面的全国性研究。我们的目的是探讨中国1-7岁儿童临床诊断的AD患病率。从中国不同地区选出了12个大都市。每个地区随机选取4-10所幼儿园和2-5所疫苗接种诊所。由皮肤科医生进行完整的病史记录和皮肤检查。AD的明确诊断和严重程度由两到三名皮肤科医生确定。详细记录了英国诊断标准所涉及的所有标准、AD的特征性表现和非典型表现。共有来自84所幼稚园及40间疫苗接种诊所的13998名儿童参与。皮肤科医生临床诊断总体AD患病率为12.94%，其中轻度AD患病率为74.6%。相比之下，基于英国诊断标准的AD患病率为4.76%。这是对中国1-7岁儿童进行的第一次面对面的全国性研究，揭示了AD在儿童中的患病率更接近富裕国家。
Prevalence of atopic dermatitis (AD) is increasing worldwide. Up to date, there has been no face-to-face nation-wide study in China. We aim to explore the prevalence of clinical diagnosed AD in children aged 1–7 ys in China. Twelve metropolises were chosen from different areas of China. In each region, we selected 4–10 kindergartens and 2–5 vaccination clinics randomly. A complete history-taking and skin examination were performed by dermatologists. The definite diagnosis of AD and the severity were determined by two or three dermatologists. All criteria concerned in UK diagnosis criteria, characteristic presentation of AD and atypical manifestations were recorded in detail. A total of 13998 children from 84 kindergartens and 40 vaccination clinics were included. The prevalence of AD was 12.94% by clinical diagnosis of dermatologists overall, with 74.6% of mild AD. Comparatively, prevalence of AD based on UK diagnostic criteria was 4.76%. This is the first face-to-face nation-wide study in Chinese children aged 1–7 ys, revealing that the prevalence of AD in children is closer to that of wealthier nations.