Ghrelin, corticosterone and the resumption of migration from stopover, an automated telemetry study
Ghrelin, corticosterone and the resumption of migration from stopover, an automated telemetry study
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DOI：
10.1016/j.physbeh.2018.06.036
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发表时间：
2018-10-01
影响因子：
2.9
通讯作者：
Kaiya, Hiroyuki
中科院分区：
文献类型：
--
作者：
Eikenaar, Cas;Hessler, Sven;Kaiya, Hiroyuki
鸟类迁徙这一壮观的自然现象显然是由物理因素塑造的，但我们对其中的生理调节却知之甚少。这一对比在移徙航班的离开过程中尤为明显。恢复迁移的决定是由一系列来自先天节律的偏离线索以及内在和外在因素形成的。目前看来，这些离开的线索被皮质酮激素转化为实际的离开，但其他激素也可能发挥作用，并可能与皮质酮相互作用。我们抓住了这个概念，在这里通过调查激素生长激素释放肽的作用和它的相互作用与皮质酮的出发决定在迁徙鸣禽。Ghrelin是一种调节食欲的激素。也有人建议，通过上调准备离开的移民的皮质酮，并通过促进脂质的分解来为移民飞行提供燃料，从而参与对离开的调节。我们测量了血浆生长激素和皮质酮水平在迁徙常见的黑鸟（Turdus merula）在秋季中途停留的网站，并确定其出发时间与使用一个全自动的无线电遥测系统。与我们的预期相反，ghrelin水平与鸟类的脂质储存或皮质酮水平无关。此外，出发可能性和夜间出发时间与胃饥饿素水平无关。因此，我们的研究并不支持ghrelin参与调节中途停留的观点，至少在普通黑鸟中没有。我们讨论了我们的期望缺乏确认的可能原因。
The spectacular natural phenomenon of avian migration is evidently shaped by physical factors, but we know little about the underlying physiological regulation. This contrast is especially apparent for the process of departure on a migratory flight. The decision to resume migration is shaped by a suite of departure cues from innate rhythms, and intrinsic and extrinsic factors. It currently appears that these departure cues are translated into actual departure by the hormone corticosterone, but other hormones may play a role too and probably interact with corticosterone. We captured this concept here by investigating the role of the hormone ghrelin and its interaction with corticosterone for the departure decision in a migratory songbird. Ghrelin functions as an appetite-regulating hormone. It has also been suggested to be involved in the regulation of departure by up regulating corticosterone in migrants ready to depart, and by facilitating the breakdown of lipids to fuel migratory flight. We measured plasmatic ghrelin and corticosterone levels in migrating common blackbirds (Turdus merula) at an autumnal stopover site, and determined their departure timing with the use of a fully-automated radio-telemetry system. Against our expectations, ghrelin level was not correlated with the birds' lipid stores or with corticosterone level. Furthermore, departure likelihood and nocturnal departure time were not associated with ghrelin levels. Our study thus does not support the idea that ghrelin is involved in the regulation of departure from stopover, at least not in common blackbirds. We discuss possible reasons for the lack of confirmation of our expectations.