ARCHAEBACTERIA AND EUKARYOTES POSSESS DNA-DEPENDENT RNA-POLYMERASES OF A COMMON TYPE
ARCHAEBACTERIA AND EUKARYOTES POSSESS DNA-DEPENDENT RNA-POLYMERASES OF A COMMON TYPE
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DOI：
10.1002/j.1460-2075.1983.tb01583.x
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发表时间：
1983-01-01
期刊：
影响因子：
11.4
通讯作者：
ZILLIG, W
中科院分区：
文献类型：
--
作者：
HUET, J;SCHNABEL, R;ZILLIG, W
古细菌的dna依赖RNA聚合酶不仅在其复杂的组分模式上类似于真核生物的核RNA聚合酶而不是真核细菌的酶，而且在单一组分水平上与真核生物的聚合酶表现出惊人的免疫化学，即结构同源性。因此，真核生物和古细菌的RNA聚合酶确实是同一类型的，不同于真核细菌的酶，真核细菌的酶也来源于一个共同的祖先结构。
DNA-dependent RNA polymerases of archaebacteria not only resemble the nuclear RNA polymerases of eukaryotes rather than the eubacterial enzymes in their complex component patterns but also show striking immunochemical, i.e., structural, homology with the eukaryotic polymerases at the level of single components. Thus, eukaryotic and archaebacterial RNA polymerases are indeed of the same type, distinct from the eubacterial enzymes, which are also derived from a common ancestral structure.