Unconstrained three-dimensional reaching in rhesus monkeys.
Unconstrained three-dimensional reaching in rhesus monkeys.
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DOI：
10.1007/s00221-010-2514-x
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发表时间：
2011-03
影响因子：
2
通讯作者：
Edgerton, V. Reggie
中科院分区：
文献类型：
--
作者：
Jindrich, Devin L.;Courtine, Gregoire;Liu, James J.;McKay, Heather L.;Moseanko, Rod;Bernot, Timothy J.;Roy, Roland R.;Zhong, Hui;Tuszynski, Mark H.;Edgerton, V. Reggie
为了更好地了解损伤后运动恢复的定量评估的规范行为，我们研究了未受伤的恒河猴在食物检索任务中的手臂运动。当猴子坐着的时候，它们会伸手去抓食物。我们记录了三维运动学和肌肉活动，并使用逆动力学来计算由于重力、节段相互作用以及手臂肌肉和组织引起的关节力矩。端点路径在三维中显示曲率，这表明保持直线路径并不是一个重要的约束。关节力矩由重力控制。广义肌肉力矩和相互作用力矩小于重力力矩的一半。肩关节和肘关节合力力矩之间的关系是线性的。虽然伸手和收回都需要肘关节屈肌力矩，但肘关节伸肌（肱三头肌）在两个阶段都是活跃的。肘部和手的拮抗肌肉在伸手和收回过程中被共同激活。节点行为可以用类似于节点扭转弹簧的集总参数模型来描述。在相互作用力矩的帮助下，关节准刚度特性的微小变化导致在重力影响下演变的互反运动。在猴子中发现的到达、抓住和取回物品的策略将允许量化脊髓损伤后恢复期间的抓握能力和治疗干预的有效性。
To better understand normative behavior for quantitative evaluation of motor recovery after injury, we studied arm movements by non-injured Rhesus monkeys during a food-retrieval task. While seated, monkeys reached, grasped, and retrieved food items. We recorded three-dimensional kinematics and muscle activity, and used inverse dynamics to calculate joint moments due to gravity, segmental interactions, and to the muscles and tissues of the arm. Endpoint paths showed curvature in three dimensions, suggesting that maintaining straight paths was not an important constraint. Joint moments were dominated by gravity. Generalized muscle and interaction moments were less than half of the gravitational moments. The relationships between shoulder and elbow resultant moments were linear during both reach and retrieval. Although both reach and retrieval required elbow flexor moments, an elbow extensor (triceps brachii) was active during both phases. Antagonistic muscles of both the elbow and hand were co-activated during reach and retrieval. Joint behavior could be described by lumped-parameter models analogous to torsional springs at the joints. Minor alterations to joint quasi-stiffness properties, aided by interaction moments, result in reciprocal movements that evolve under the influence of gravity. The strategies identified in monkeys to reach, grasp, and retrieve items will allow the quantification of prehension during recovery after a spinal cord injury and the effectiveness of therapeutic interventions.
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影响因子：
2.5
作者：
FISK, J;LACKNER, JR;DIZIO, P
通讯作者：
DIZIO, P
影响因子：
2
作者：
Dounskaia, N;Wisleder, D;Johnson, T
通讯作者：
Johnson, T
影响因子：
2.5
作者：
Gribble, PL;Ostry, DJ
通讯作者：
Ostry, DJ
影响因子：
3.3
作者：
Gentili, R.;Cahouet, V.;Papaxanthis, C.
通讯作者：
Papaxanthis, C.
影响因子：
2.5
作者：
Gottlieb, GL;Song, QL;Corcos, D
通讯作者：
Corcos, D