Carbon dioxide potentiates the mitogenic effects of nicotine and its carcinogenic derivative, NNK, in normal and neoplastic neuroendocrine lung cells via stimulation of autocrine and protein kinase C-dependent mitogenic pathways.
Carbon dioxide potentiates the mitogenic effects of nicotine and its carcinogenic derivative, NNK, in normal and neoplastic neuroendocrine lung cells via stimulation of autocrine and protein kinase C-dependent mitogenic pathways.
复制标题
二氧化碳通过刺激自分泌和蛋白激酶 C 依赖性有丝分裂途径,增强尼古丁及其致癌衍生物 NNK 在正常和肿瘤性神经内分泌肺细胞中的促有丝分裂作用。
作者:
Schuller,HM