Thelazia eyeworm:: an original endo- and ecto-parasitic nematode
Thelazia eyeworm:: an original endo- and ecto-parasitic nematode
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DOI：
10.1016/j.pt.2004.10.008
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发表时间：
2005-01-01
影响因子：
9.6
通讯作者：
Traversa, D
中科院分区：
文献类型：
--
作者：
Otranto, D;Traversa, D
Thelazia属由几种寄生虫组成，通常被称为眼虫，它们感染哺乳动物的眼睛和相关组织，包括人类。眼虫的传播是通过以动物的眼分泌物、泪水和结膜为食的非叮咬双翅目昆虫进行的。这种疾病是一种以一系列亚临床到临床症状为特征的疾病，如溢泪、结膜炎、角膜炎、角膜混浊和溃疡。在许多亚洲国家的贫穷社会经济环境中，人类齐齐病很常见。这里讨论了眼虫和它们的宿主之间的关系，以及最新的分子洞察力，这些见解有助于在它们的最终和中间宿主中研究丝虫的生物学。
The genus Thelazia comprises several parasites, commonly named eyeworms, which infect the eyes and associated tissues of mammals, including humans. Transmission of eyeworms occurs via non-biting diptera that feed on the ocular secretions, tears and conjunctiva of animals. The disease, thelaziosis, is characterized by a range of subclinical to clinical signs, such as epiphora, conjunctivitis, keratitis, corneal opacity and ulcers. Human thelaziosis is common in poor socio-economic settings in many Asian countries. The relationship between eyeworms and their hosts are discussed here, together with recent molecular insights that are instrumental in investigating the biology of Thelazia in their definitive and intermediate hosts.