Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States

Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States
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DOI:
10.1128/aac.00158-08
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发表时间:
2008-07-01
影响因子:
4.9
通讯作者:
Bonomo, Robert A.
Bonomo, Robert A.
中科院分区:
医学2区
文献类型:
--
作者:
Endimiani, Andrea;Carias, Lenore L.;Bonomo, Robert A.

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本研究对美国东部地区42株肺炎克雷伯菌(KpC)的耐喹诺酮基因[即qnrA、qnrB、qnrS、aac(6‘)-Ib-cr和qepA]的存在进行了评估。其中一株携带bla(kpc-3)和qnrB19基因,另一株携带bla(kpc-3)和qnrA1基因。
The presence of plasmid-mediated quinolone resistance genes [i.e., qnrA, qnrB, qnrS, aac(6')-Ib-cr, and qepA] was evaluated among 42 bla(KPC)-containing Klebsiella pneumoniae isolates collected in the eastern United States. One isolate carried the bla(KPC-3) and qnrB19 genes on the same conjugative plasmid, whereas another carried the bla(KPC-3) and qnrA1 genes on separate plasmids.