HIV-1 CRF_BC Recombinants Infection in China: Molecular Epidemic and Characterizations
HIV-1 CRF_BC Recombinants Infection in China: Molecular Epidemic and Characterizations
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中国 HIV-1 CRF_BC 重组体感染：分子流行病和特征
DOI：
10.2174/157016212799937236
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发表时间：
2012-03-01
影响因子：
1
通讯作者：
Ma, Liying
中科院分区：
文献类型：
--
作者：
Ouyang, Yabo;Shao, Yiming;Ma, Liying
CRF_BC重组毒株首先在中国发现，是中国最流行和最具特征的HIV-1亚型之一。本文综述了HIV-1CRF_BC重组病毒在中国的流行情况，并对其遗传学、生物学和耐药性进行了分析。本研究有助于更好地了解中国HIV-1CRF_BC的流行现状，促进疫苗和更有效的抗HIV-1治疗方案的开发。
CRF_BC recombinant strains were first identified in China and are one of the most prevalent and characteristically unique HIV-1 subtypes across China. Here we aim to review the published data about HIV-1 CRF_BC recombinant strains epidemic in China and to characterize the genetics, biology and drug resistance of this virus. This study may help to better understand the current situation of HIV-1 CRF_BC prevalence and facilitate the development of vaccines and more efficient anti-HIV-1 regimens in China.