COHERENT 25-HZ TO 35-HZ OSCILLATIONS IN THE SENSORIMOTOR CORTEX OF AWAKE BEHAVING MONKEYS
COHERENT 25-HZ TO 35-HZ OSCILLATIONS IN THE SENSORIMOTOR CORTEX OF AWAKE BEHAVING MONKEYS
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DOI：
10.1073/pnas.89.12.5670
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发表时间：
1992-06-15
影响因子：
11.1
通讯作者：
FETZ, EE
中科院分区：
文献类型：
--
作者：
MURTHY, VN;FETZ, EE
同步25- 35-Hz振荡观察到在清醒的恒河猴的感觉运动皮层的局部场电位和单位活动。振荡事件经常发生时，猴子检索葡萄干从Kluver板或从看不见的位置使用体感反馈;他们很少发生在重复的手腕屈曲和伸展运动的性能。振荡的幅度，持续时间和频率没有直接相关的运动参数的行为研究到目前为止。振荡的发生并不总是与前臂肌肉的活动爆发有关，但周期触发的平均肌电图显示屈肌和伸肌的同步调制。振荡的相位从皮层的表层到深层不断变化，在超过800 μ m的深度完全反转其极性。在中央前皮质，这种振荡在14 mm左右的距离上可以变得同步。相干振荡也可能发生在前和postcentral网站分开的估计切线皮质内距离为20毫米。活动的单个单位通常被视为突发同步与场电位振荡。这些发现表明，这种振荡可能有助于细胞之间的相互作用，在探索和操纵运动，需要注意感觉运动整合。
Synchronous 25- to 35-Hz oscillations were observed in local field potentials and unit activity in sensorimotor cortex of awake rhesus monkeys. The oscillatory episodes occurred often when the monkeys retrieved raisins from a Kluver board or from unseen locations using somatosensory feedback; they occurred less often during performance of repetitive wrist flexion and extension movements. The amplitude, duration, and frequency of oscillations were not directly related to movement parameters in behaviors studied so far. The occurrence of the oscillations was not consistently related to bursts of activity in forearm muscles, but cycle-triggered averages of electromyograms revealed synchronous modulation in flexor and extensor muscles. The phase of the oscillations changed continuously from the surface to the deeper layers of the cortex, reversing their polarity completely at depths exceeding 800-mu-m. The oscillations could become synchronized over a distance of 14 mm mediolaterally in precentral cortex. Coherent oscillations could also occur at pre- and postcentral sites separated by an estimated tangential intracortical distance of 20 mm. Activity of single units was commonly seen to burst in synchrony with field potential oscillations. These findings suggest that such oscillations may facilitate interactions between cells during exploratory and manipulative movements, requiring attention to sensorimotor integration.