Antibiotic Resistance Genes Online (ARGO): a Database on vancomycin and beta-lactam resistance genes.
Antibiotic Resistance Genes Online (ARGO): a Database on vancomycin and beta-lactam resistance genes.
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DOI：
10.6026/97320630001005
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发表时间：
2005-03-17
期刊：
影响因子：
1.9
通讯作者：
Verma SK
中科院分区：
文献类型：
--
作者：
Scaria J;Chandramouli U;Verma SK
万古霉素和β -内酰胺是通过干扰细胞壁合成抑制革兰氏阳性菌的抗生素。然而，持续使用抗生素导致多重耐药（MDR）菌株的出现。在这里，我们描述了ARGO，一个包含赋予这两类抗生素耐药性的基因序列的数据库。它旨在作为一种资源，加强对抗生素耐药基因的流行和传播的研究。ARGO是第一次尝试编制具有国家特定信息的抗性基因序列数据。AGRO可以在http://www.argodb.org/上免费获得
Vancomycin and βlactams are antibiotics that inhibit gram positive bacteria by interfering with cell wall synthesis. However, continuous use of antibiotics results in the emergence of multi-drug resistant (MDR) bacterial strains. Here, we describe ARGO, a database containing gene sequences conferring resistance to these two classes of antibiotics. It is designed as a resource to enhance research on the prevalence and spread of antibiotic resistance genes. ARGO is the first attempt to compile the resistance gene sequence data with state specific information. AGRO is available for free at http://www.argodb.org/