Complement Receptor 3-Like Immunoreactivity in the Superior and Inferior Tentacles of Terrestrial Slug, Limax marginatus

Complement Receptor 3-Like Immunoreactivity in the Superior and Inferior Tentacles of Terrestrial Slug, Limax marginatus
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陆生蛞蝓上触手和下触手中补体受体 3 样免疫反应性

DOI:
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发表时间:
2001
期刊:
影响因子:
--
通讯作者:
E. Ito
E. Ito
中科院分区:
--
文献类型:
--
作者:
D. Hatakeyama;I. Ito;E. Ito

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摘要 补体受体3(CR3)是细胞粘附分子之一,在哺乳动物中性粒细胞的分泌中起着至关重要的作用。为了研究 CR3 是否也参与腹足类软体动物的神经分泌,我们检测了陆生蛞蝓 Limax marginatus 的中枢神经系统 (CNS) 和上触手和下触手中的 CR3 样免疫反应性。在边缘乳杆菌的中枢神经系统中,我们根本没有检测到特异性免疫反应性。相反,在上触手和下触手的领细胞的细胞体和突起中观察到CR3样免疫反应性。特别是,领细胞的细胞体中含有的颗粒表现出CR3样免疫反应性。将辣根过氧化物酶逆行标记应用于上触手和下触手的感觉上皮 (SE) 上,结果表明这些触手的领细胞将其突起投射到 SE 上。在之前的研究中,将上触手的匀浆注射到蛞蝓体腔中可以刺激精子发生,同时抑制产卵行为,这表明触手激素具有促性腺激素的作用。综上所述,在边缘细胞中表达的CR3被认为参与了L.marginatus触手激素的分泌。
Abstract Complement receptor 3 (CR3), one of cell adhesion molecules, plays a crucial role in secretion of mammalian neutrophils. To study whether CR3 is also involved in neurosecretion of gastropod molluscs, we examined the CR3-like immunoreactivity in the central nervous system (CNS) and the superior and inferior tentacles of the terrestrial slug, Limax marginatus. In the CNS of L. marginatus, we did not detect the specific immunoreactivity at all. In contrast, the CR3-like immunoreactivity was observed in the cell bodies and processes of collar cells of the superior and inferior tentacles. In particular, granules contained in the cell bodies of collar cells exhibited the CR3-like immunoreactivity. Retrograde labeling of horseradish peroxidase applied on the sensory epithelia (SE) of superior and inferior tentacles showed that the collar cells of these tentacles project their processes to the SE. In the previous study, homogenate of the superior tentacles injected into the body cavity of slugs stimulated spermatogenesis and simultaneously inhibited egg-laying behavior, suggesting that the tentacular hormone acts as gonadotropic hormone. Taken together, CR3 expressed in the collar cells is considered to be involved in the secretion of tentacular hormone in L. marginatus.
中性粒细胞 CR3 表达和特异性颗粒胞吐作用由不同的信号转导途径控制。
DOI: --
发表时间: 1991
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Brown,GE;Reed,EB;Lanser,ME
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龙虾中枢神经系统中章鱼胺免疫反应神经元的定位。
DOI: 10.1002/cne.903290109
发表时间: 1993
期刊: The Journal of comparative neurology
影响因子: --
作者:
Schneider,H;Trimmer,BA;Rapus,J;Eckert,M;Valentine,DE;Kravitz,EA
通讯作者: Kravitz,EA
佛波酯在中性粒细胞中的特定颗粒胞吐作用位点诱导功能性、新表达的 CR3 的瞬时焦点浓度。
DOI: --
发表时间: 1991
影响因子: 6.6
作者:
Pryzwansky,KB;Wyatt,T;Reed,W;Ross,GD
通讯作者: Ross,GD