Selective reduction of nitro-compounds to primary amines by nickel-catalyzed hydrosilylative reduction
Selective reduction of nitro-compounds to primary amines by nickel-catalyzed hydrosilylative reduction
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作者：
Ni（acac）_2和PMHS是一种优良的硝基化合物化学选择性转移氢化为伯胺的催化体系。在温和的条件下，一系列含有醛、酯、氰基、硝基等敏感官能团的硝基化合物被还原成相应的胺类化合物，产率高，无副产物。
Ni(acac)2 and PMHS were found to be an excellent catalytic system for the chemoselective transfer hydrogenation of nitro-compounds to primary amines. Under mild conditions a series of nitro-compounds containing a variety of sensitive functional groups including aldehydes, esters, cyano, and nitrine were reduced to their corresponding amines in good to excellent yields with no byproduct.