Brain potentials reflect residual face processing in a case of prosopagnosia
Brain potentials reflect residual face processing in a case of prosopagnosia
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DOI：
10.1080/02643290342000258
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发表时间：
2004-10-01
影响因子：
3.4
通讯作者：
Valdés-Sosa, M
中科院分区：
文献类型：
--
作者：
Bobes, MA;Lopera, F;Valdés-Sosa, M
此处，ERP 用于表征 FE 的残余面部加工特征，该患者的腹侧颞枕皮质严重受损，并且面容失认严重。 Alarge N170出现在FE中，并且在面部结构处理测试中表现出色。 P300 古怪的实验证明了对熟人面孔的秘密识别。 P300 效应的起始潜伏期正常，表明隐蔽记忆的快速可用性。 FE 中该部分的头皮地形与 P3b 的头皮地形不同，呈现出中央额叶最大值。 FE 对熟悉面孔的皮肤电导反应也比对不熟悉面孔的皮肤电导反应更大。单次试验 P300 和熟悉面孔触发的 SCR 的幅度均与 FE 对装腔作势者的熟悉程度呈正相关。当要求他根据明确的认知在熟悉的人的面孔和陌生的人的面孔之间进行选择时，他的表现是偶然的，而如果被迫选择是基于可信度或模糊的熟悉感，他会更多地选择以前认识的面孔。结果表明，在 FE 中，早期人脸处理相对完整，隐蔽识别速度很快。涉及情感或社交线索处理的神经结构可能介导 FE 中存在的隐蔽识别。
Here, ERPs were employed to characterise the residual face processing of FE, a patient with extensive damage to the ventral temporal-occipital cortex and a dense prosopagnosia. Alarge N170 was present in FE and he performed well in tests of face structural processing. Covert recognition of the faces of personal acquaintances was demonstrated with P300 oddball experiments. The onset latency of the P300 effect was normal, indicating fast availability of covert memory. The scalp topography of this component in FE was different from that of the P3b, presenting a centro-frontal maximum. FE also presented larger skin conductance responses to familiar than to unfamiliar faces. The amplitudes of both the single-trial P300s and the SCRs triggered by familiar faces were positively correlated with the degree of person-familiarity that FE had for the poser. He performed at chance when asked to select between the face of a familiar person and that of an unfamiliar person on the basis of explicit recognition, whereas he selected more the previously known face if the forced choice was based on trustworthiness or a vague sense of familiarity. The results suggest that in FE, early face processing was relatively intact and covert recognition was fast. Neural structures involved in the processing of emotional or social cues possibly mediate the covert recognition present in FE.