Factors affecting graft infection after cranioplasty
Factors affecting graft infection after cranioplasty
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DOI：
10.1016/j.jocn.2007.09.022
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发表时间：
2008-10-01
影响因子：
2
通讯作者：
Chang, Chen-Nen
中科院分区：
文献类型：
--
作者：
Cheng, Yu-Kai;Weng, Hsu-Huei;Chang, Chen-Nen
本研究的目的是确定颅骨成形术后骨移植物感染相关的危险因素。 2002年至2006年期间，对75名患者进行了84例颅骨成形术。第1组使用冷冻骨移植物作为移植材料，第2组使用聚甲基丙烯酸甲酯（PMMA）。比较组间的危险因素，包括年龄、性别、开颅手术和颅骨成形术之间的时间间隔、损伤机制、手术次数、移植材料和格拉斯哥昏迷量表评分。拭子培养结果和骨移植物感染评估为病组1。颅骨成形术前多次手术以及颅骨切除术和颅骨成形术之间的时间间隔不足会增加颅骨成形术后感染的风险。拭子培养结果、年龄、性别、损伤机制、移植材料和格拉斯哥昏迷量表评分与感染无关。使用 PMMA 的感染风险相对较低 (6.25%)。在本研究中，风险或移植物感染与移植材料的选择无关。多次手术和时间间隔不足会增加感染风险。中断伤口愈合过程可能是感染的原因。无论以前是否感染过，PMMA 都是颅骨成形术的安全材料。 (c) 2007 年，爱思唯尔有限公司出版。
The aim of this study was to identify the risk factors associated with bone grafts infection after cranioplasty. Eighty-four cranioplasties were performed oil 75 patients between 2002 and 2006. Cryopreserved bone grafts were used as graft material in group 1 and polymethylmethacrylate (PMMA) was used in group 2. Risk factors including age, gender, time intervals between craniectomy and cranioplasty, mechanism of injury, number of procedures, graft material, and the Glasgow Coma Scale score were compared between groups. Swab culture results and bone graft infection were assessed ill group 1. Multiple procedures before cranioplasty and an inadequate time interval between craniectomy and cranioplasty increase the risk of infection after cranioplasty. Swab culture results, age, gender, mechanism Of injury, graft material and Glasgow Coma Scale score are not related to infection. The use of PMMA was associated with a relatively low risk of infection (6.25%). Risk or graft infection was not associated with the choice of graft material in the present study. Multiple procedures and insufficient time intervals increase the risk of infection. Interrupting the wound healing process may be the cause of infection. PMMA is a safe material for cranioplasty regardless of previous infection. (c) 2007 Published by Elsevier Ltd.