Neuronal implementation of hippocampal-mediated spatial behavior: a comparative evolutionary perspective.
Neuronal implementation of hippocampal-mediated spatial behavior: a comparative evolutionary perspective.
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DOI：
10.1177/1534582306289578
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发表时间：
2006-06-01
期刊：
影响因子：
--
通讯作者：
Sharp, Patricia E
中科院分区：
文献类型：
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作者：
Bingman, Verner P;Sharp, Patricia E
哺乳动物和鸟类的海马结构（HF）在空间表征中起着惊人相似的作用。然而，这种进化上保守的属性，掩盖了对比空间生态的动物，如大鼠和信鸽，不同的空间生态，应该有促进组特异性适应HF表示空间的进化。然而，鸽子和大鼠HF神经元的空间响应特性揭示了位置，方向和轨迹对解释放电率的空间变化的贡献惊人的相似性。相比之下，信鸽（而非大鼠）左右HF中神经元反应特性的不对称分布表明网络组织的差异。作者提出，海马进化的特点可能是相对于决定神经元反应特性的基本空间元素的变化的惯性，但在神经元反应元素如何组织成功能网络方面具有相当大的可塑性。
The hippocampal formation (HF) of mammals and birds plays a strikingly similar role in the representation of space. This evolutionarily conserved property, however, belies the contrasting spatial ecology of animals such as rats and homing pigeons, differing spatial ecologies that should have promoted the evolution of group-specific adaptations to the HF representation of space. However, the spatial response properties of pigeon and rat HF neurons reveal surprising similarity in the contribution of position, direction, and trajectory toward explaining spatial variation in firing rate. By contrast, the asymmetrical distribution of neuronal response properties in the left and right HF of homing pigeons, but not rats, indicates a difference in network organization. The authors propose that hippocampal evolution may be characterized by inertia with respect to changes in the basic spatial elements that determine the response properties of neurons but considerable plasticity in how the neuronal response elements are organized into functional networks.