The stringent response genes relA and spoT are important for Escherichia coli biofilms under slow-growth conditions

The stringent response genes relA and spoT are important for Escherichia coli biofilms under slow-growth conditions
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DOI:
10.1139/w02-060
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发表时间:
2002-07-01
影响因子:
2.8
通讯作者:
McLean, RJC
McLean, RJC
中科院分区:
生物学4区
文献类型:
--
作者:
Balzer, GJ;McLean, RJC

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为了观察严格反应是否参与生物膜形成,在丝氨酸限制下,将大肠杆菌DS 291(MG 1655)及其等基因relA spoT衍生物在恒化器中以0.025和0.25 h(-1)的稀释率生长48 h。严格的反应基因relA和spoT的情况下几乎没有影响的反渗透细胞浓度。一个重要的(P
In order to see whether the stringent response was involved in biofilm formation, Escherichia coli DS291 (MG1655), and its isogenic relA spoT derivative were grown for 48 h in a chemostat at dilution rates of 0.025 and 0.25 h(-1) under serine limitation. The absence of the stringent response genes relA and spoT had little effect on the planktonic cell concentrations. However, a significant (P