Engineering strategies of Anti-HIV antibody therapeutics in clinical development.
Engineering strategies of Anti-HIV antibody therapeutics in clinical development.
复制标题
抗HIV抗体疗法在临床开发中的工程策略。
DOI:
10.1097/coh.0000000000000796
复制
发表时间:
2023
影响因子:
4.1
通讯作者:
Bournazos,Stylianos
中科院分区:
文献类型:
--
作者:
Pihlstrom,Nicole;Bournazos,Stylianos
The development of Fc and Fab-engineered antibodies for the treatment of HIV continues to show promising progress. These novel therapies have the potential to overcome the limitations of current antiretroviral pharmacologic agents by more effectively suppressing viral load and targeting latent reservoirs in individuals living with HIV. Further studies are needed to fully understand the safety and efficacy of these therapies, but the growing body of evidence supports their potential as a new class of therapeutics for the treatment of HIV.