Influences of breathing patterns on respiratory sinus arrhythmia in humans during exercise
Influences of breathing patterns on respiratory sinus arrhythmia in humans during exercise
复制标题
DOI：
10.1152/ajpheart.00767.2004
复制
发表时间：
2005-02-01
影响因子：
4.8
通讯作者：
Bermon, S
中科院分区：
文献类型：
--
作者：
Blain, G;Meste, O;Bermon, S
据报道，人类在剧烈运动期间会出现持续性呼吸性窦性心律失常（RSA），这归因于通气量的增加。然而，通风对 RSA 的直接影响从未被评估过。使用原始建模方法对 14 名健康男性运动期间 RSA 的动态演变及其与通气的联系进行了研究。根据去趋势和高通滤波的心脏周期序列估计进化模型。然后从所有记录中提取瞬时 RSA 频率（F-RSA，以 Hz 为单位）和幅度（A(RSA)，以 ms 为单位）。 A(RSA)通过短时傅立叶变换计算。首先，根据分级和最大运动测试期间获得的数据进行 F-RSA 和 A(RSA) 的测量。然后在次最大[70% 峰值 O-2 消耗（(V) 超过点 O-2peak）] 矩形运动回合中测试不同通气方案 [潮气量 (V-T) 和呼吸频率 (F-R) 的变化] 对 A(RSA) 的影响。在分级和最大运动条件下，A(RSA) 从运动开始下降到点 O-2peak 的 61.9 +/- 3.8% (V)，然后增加直至运动峰值。在定速呼吸方案期间，正常通气 (69.4 +/- 8.8 l/min)、过度通气 (81.8 +/- 8.3 l/min) 和通气不足 (56.4 +/- 6.2 l/min) 导致显着 ( P < 0.01) 不同的 A(RSA) 值（3.8 +/- 0.5、4.6 +/- 0.8 和 2.9 +/-分别为 0.5 毫秒）。此外，当通气量保持恒定时，无论 F-R-V-T 组合如何，A(RSA) 均未发现统计学差异。这些结果表明，RSA 在所有运动强度下均持续存在，并在最高强度下增加。它的持续性和增加与肺充气的频率和程度密切相关，表明呼吸对 RSA 具有机械影响。
Persistence of respiratory sinus arrhythmia ( RSA) has been described in humans during intense exercise and attributed to an increase in ventilation. However, the direct influence of ventilation on RSA has never been assessed. The dynamic evolution of RSA and its links to ventilation were investigated during exercise in 14 healthy men using an original modeling approach. An evolutive model was estimated from the detrended and high-pass-filtered heart period series. The instantaneous RSA frequency (F-RSA, in Hz) and amplitude (A(RSA), in ms) were then extracted from all recordings. A(RSA) was calculated with short-time Fourier transform. First, measurements of F-RSA and A(RSA) were performed from data obtained during a graded and maximal exercise test. Influences of different ventilation regimens [ changes in tidal volume (V-T) and respiratory frequency (F-R)] on A(RSA) were then tested during submaximal [70% peak O-2 consumption ((V) over dot O-2peak)] rectangular exercise bouts. Under graded and maximal exercise conditions, A(RSA) decreased from the beginning of exercise to 61.9 +/- 3.8% (V) over dot O-2peak and then increased up to peak exercise. During the paced breathing protocol, normoventilation (69.4 +/- 8.8 l/min), hyperventilation (81.8 +/- 8.3 l/min), and hypoventilation (56.4 +/- 6.2 l/min) led to significantly ( P < 0.01) different A(RSA) values (3.8 +/- 0.5, 4.6 +/- 0.8, and 2.9 +/- 0.5 ms, respectively). In addition, no statistical difference was found in A(RSA) when ventilation was kept constant, whatever the F-R-V-T combinations. Those results indicate that RSA persists for all exercise intensities and increases during the highest intensities. Its persistence and increase are strongly linked to both the frequency and degree of lung inflation, suggesting a mechanical influence of breathing on RSA.