Repeated Measurements of Hepatitis B Surface Antigen Identify Carriers of Inactive HBV During Long-term Follow-up
Repeated Measurements of Hepatitis B Surface Antigen Identify Carriers of Inactive HBV During Long-term Follow-up
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DOI：
10.1016/j.cgh.2016.01.019
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发表时间：
2016-10-01
影响因子：
12.6
通讯作者：
Hansen, Bettina E.
中科院分区：
文献类型：
--
作者：
Brouwer, Willem P.;Chan, Henry Lik-Yuen;Hansen, Bettina E.
背景与目的：检测B型肝炎表面抗原（HBsAg）和B型肝炎病毒（HBV）DNA有助于鉴别非活动性HBV携带者。我们评估了重复测量HBsAg的性能超过了一个中位数的时间段为8 years.METHODS：我们进行了一项回顾性研究，292例HBe抗原阴性的慢性HBV感染患者，丙氨酸氨基转移酶（ALT）水平正常，HBV DNA水平100 IU/mL的HBV活动在第三年。结合HBsAg水平
BACKGROUND & AIMS: Measurements of hepatitis B surface antigen (HBsAg) and hepatitis B virus (HBV) DNA might help to identify carriers of inactive HBV. We assessed the performance of repeated measurements of HBsAg over a median time period of 8 years.METHODS: We performed a retrospective study of 292 HBe antigen-negative patients with chronic HBV infection, normal levels of alanine aminotransferase (ALT), levels of HBV DNA 100 IU/mL had HBV activity in the third year. The combination of HBsAg level