Electrospun Nanofibers for Periodontal Treatment: A Recent Progress.
Electrospun Nanofibers for Periodontal Treatment: A Recent Progress.
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用于牙周治疗的静电纺纳米纤维：最新进展
DOI：
10.2147/ijn.s370340
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发表时间：
2022
影响因子：
8
通讯作者：
中科院分区：
文献类型：
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作者：
摘要牙周炎是口腔健康的主要威胁，促使科学家不断研究新的治疗技术。静电纺丝法制备的纳米纤维膜具有大的比表面积和高的孔隙率。一方面，电纺纳米纤维可以提高蛋白质的吸收能力，促进特定基因的表达。另一方面，它们可以改善细胞粘附性能，防止成纤维细胞穿过屏障膜。因此，静电纺丝在牙周治疗中具有独特的优势。目前，许多具有抗菌、抗炎和组织再生特性的口腔纳米纤维膜已被制备用于牙周治疗。本文首先介绍了静电纺丝的工艺过程。总结了目前用于治疗牙周炎的静电纺纳米纤维膜的常用聚合物。最后，介绍了不同类型的纳米纤维膜通过静电纺丝制备牙周治疗，并描述了未来的发展静电纺丝治疗牙周炎。
Abstract Periodontitis is a major threat to oral health, prompting scientists to continuously study new treatment techniques. The nanofibrous membrane prepared via electrospinning has a large specific surface area and high porosity. On the one hand, electrospun nanofibers can improve the absorption capacity of proteins and promote the expression of specific genes. On the other hand, they can improve cell adhesion properties and prevent fibroblasts from passing through the barrier membrane. Therefore, electrospinning has unique advantages in periodontal treatment. At present, many oral nanofibrous membranes with antibacterial, anti-inflammatory, and tissue regeneration properties have been prepared for periodontal treatment. First, this paper introduces the electrospinning process. Then, the commonly used polymers of electrospun nanofibrous membranes for treating periodontitis are summarized. Finally, different types of nanofibrous membranes prepared via electrospinning for periodontal treatment are presented, and the future evolution of electrospinning to treat periodontitis is described.