Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range
Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range
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DOI：
10.1364/oe.17.014880
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发表时间：
2009-08-17
期刊：
影响因子：
3.8
通讯作者：
Wojtkowski, Maciej
中科院分区：
文献类型：
--
作者：
Gora, Michalina;Karnowski, Karol;Wojtkowski, Maciej
我们提出了一个应用程序在活体眼前节成像的人的眼睛与高速扫描源OCT仪器。为此，设计并构建了专用OCT系统。该仪器通过自动重新配置光谱扫描范围实现轴向缩放;增强成像范围模式实现整个前段成像，而高轴向分辨率模式提供房角和角膜的详细形态信息。200，000线/秒的速度使整个角膜的三维成像在250 ms内实现高采样密度，这使OCT在光学角膜地形图、角膜厚度测量和高程图方面的应用前景广阔。初步定量角膜分析的基础上OCT数据自由形式的运动伪影的结果。此外，体积和真实的时间重建的动态过程，如瞳孔对光刺激或闪烁引起的接触透镜运动的反应被证明。(C)2009年美国光学学会
We present an application of in vivo anterior segment imaging of the human eye with an ultrahigh speed swept source OCT instrument. For this purpose, a dedicated OCT system was designed and constructed. This instrument enables axial zooming by automatic reconfiguration of spectral sweep range; an enhanced imaging range mode enables imaging of the entire anterior segment while a high axial resolution mode provides detailed morphological information of the chamber angle and the cornea. The speed of 200,000 lines/s enables high sampling density in three-dimensional imaging of the entire cornea in 250 ms promising future applications of OCT for optical corneal topography, pachymetry and elevation maps. The results of a preliminary quantitative corneal analysis based on OCT data free form motion artifacts are presented. Additionally, a volumetric and real time reconstruction of dynamic processes, like pupillary reaction to light stimulus or blink-induced contact lens movements are demonstrated. (C) 2009 Optical Society of America