Durable chronic low back pain reductions up to 24 months after treatment for an accessible, 8-week, in-home behavioral skills-based virtual reality program: a randomized controlled trial.
Durable chronic low back pain reductions up to 24 months after treatment for an accessible, 8-week, in-home behavioral skills-based virtual reality program: a randomized controlled trial.
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DOI：
10.1093/pm/pnad070
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发表时间：
2023-10-03
期刊：
影响因子：
3.1
通讯作者：
Darnall, Beth D.
中科院分区：
文献类型：
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作者：
Maddox, Todd;Sparks, Charisse;Oldstone, Liesl;Maddox, Roselani;Ffrench, Kelsey;Garcia, Heidy;Krishnamurthy, Parthasarathy;Okhotin, David;Garcia, Laura M.;Birckhead, Brandon J.;Sackman, Josh;Mackey, Ian;Louis, Robert;Salmasi, Vafi;Oyao, Alexis;Darnall, Beth D.
方法完整的方法已经公布。11这项研究设计是由VR研究团队与斯坦福大学医学院教授Beth Darnall博士合作完成的。通过慢性疼痛组织、医疗保健专业人员和在线广告招募自我报告cLBP的个体（持续时间> 6个月，过去一个月的平均疼痛强度≥ 4，疼痛评分为0-10）。一旦同意参与，cLBP参与者将以1：1的比例随机分配到基于技能的VR计划或Sham VR。基于技能的VR计划提供了一个固定的56个VR体验序列（一次性完成），其中包括认知行为疗法，正念和疼痛神经科学教育中使用的循证自我调节技能。Sham VR提供了一个固定的56个非沉浸式的二维自然视频序列，覆盖着中性音乐。于2022年9月和10月收集了国防和退伍军人疼痛评定量表（DVPRS，DVPRS-II）的24个月治疗后数据。参与者完成调查共获得75美元。WCG机构审查委员会（Puyallup，WA，美国）于2020年7月批准了研究方案。结果168名完成治疗结束调查的参与者中有127名完成了24个月的治疗后调查（76%;基于技能的VR，n= 68/84 [81%]; Sham VR，n= 59/84 [70%]）。在基于技能的VR组和假VR组脱落者之间，或者在基于技能的VR组或假VR组内脱落者和应答者之间，未观察到人口统计学或基线临床变量的差异。人口统计学包括年龄、性别、教育、就业状况和收入。基线数据包括疼痛强度、疼痛干扰、疼痛灾难化、疼痛自我效能、PROMIS身体功能和PROMIS睡眠障碍。平均值和标准差可用于荟萃分析目的。
MethodsFull methods have been published. 11 The study design emerged from a collaboration between the AppliedVR Research team and Dr. Beth Darnall, Professor, Stanford University School of Medicine. Individuals with self-reported cLBP (duration of> 6 months and average pain intensity of≥ 4 for the past month on a 0–10 pain rating scale) were recruited through chronic pain organizations, health care professionals, and online advertisements. Once they had given their consent to participate, cLBP participants were randomized 1: 1 to the Skills-Based VR Program or to Sham VR. The Skills-Based VR Program offers a fixed sequence of 56 VR experiences (to be completed once) that incorporate evidence-based self-regulatory skills used in cognitive behavior therapy, mindfulness, and pain neuroscience education. Sham VR offers a fixed sequence of 56 non-immersive, 2-dimensional nature videos overlaid with neutral music. Twenty-four–month posttreatment data from the Defense and Veterans Pain Rating Scales (DVPRS, DVPRS-II) were collected in September and October of 2022. Participants received a total of $75 for survey completion. The WCG Institutional Review Board (Puyallup, WA, United States) approved the study protocol in July 2020.ResultsThe 24-month posttreatment surveys were completed by 127 of the 168 participants who completed the end-of-treatment surveys (76%; Skills-Based VR, n= 68 of 84 [81%]; Sham VR, n= 59 of 84 [70%]). No differences in demographic or baseline clinical variables were observed between Skills-Based VR and Sham VR dropouts or between dropouts and responders within the Skills-Based VR or Sham VR groups. Demographics included age, gender, education, employment status, and income. Baseline data included pain intensity, pain interference, pain catastrophizing, pain self-efficacy, PROMIS physical function, and PROMIS sleep disturbance. Means and standard deviations are available for meta-analytic purposes.
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影响因子：
2.9
作者：
Yang J;Lo WLA;Zheng F;Cheng X;Yu Q;Wang C
通讯作者：
Wang C
DOI：
10.1136/bmj-2021-067718
发表时间：
2022-03-30
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Ho EK;Chen L;Simic M;Ashton-James CE;Comachio J;Wang DXM;Hayden JA;Ferreira ML;Ferreira PH
通讯作者：
Ferreira PH
影响因子：
7.4
作者：
通讯作者：
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影响因子：
7.4
作者：
Garcia, Laura;Birckhead, Brandon;Krishnamurthy, Parthasarathy;Mackey, Ian;Sackman, Josh;Salmasi, Vafi;Louis, Robert;Castro, Carina;Maddox, Roselani;Maddox, Todd;Darnall, Beth
通讯作者：
Darnall, Beth
影响因子：
1.7
作者：
Garcia LM;Darnall BD;Krishnamurthy P;Mackey IG;Sackman J;Louis RG;Maddox T;Birckhead BJ
通讯作者：
Birckhead BJ