Reduced plasma ACE2 activity in dialysis patients: another piece in the conundrum of factors involved in hypertension and cardiovascular morbidity?
Reduced plasma ACE2 activity in dialysis patients: another piece in the conundrum of factors involved in hypertension and cardiovascular morbidity?
复制标题
透析患者血浆 ACE2 活性降低：高血压和心血管发病因素相关因素难题中的另一部分？
DOI：
10.1093/ndt/gft240
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Batlle,Daniel
中科院分区：
文献类型：
--
作者：
Wysocki,Jan;Batlle,Daniel
据报道，接受透析治疗的终末期肾病患者血浆血管紧张素转换酶2活性降低，特别是在女性受试者中，可能会限制血管紧张素转换酶II的降解，导致血管紧张素转换酶II水平升高，这可能导致困扰透析人群的高血压和心血管疾病的高发。
the reduction in plasma ACE2 activity reported in ESRD patients treated by dialysis, particularly in female subjects, could limit Ang II degradation leading to increased levels of this peptide, which could contribute to the high prevalence of hypertension and cardiovascular morbidity that afflicts the dialysis population