The use of E/Em and the time interval difference of isovolumic relaxation (TIVRT-IvRTm) in estimating left ventricular filling pressures
The use of E/Em and the time interval difference of isovolumic relaxation (TIVRT-IvRTm) in estimating left ventricular filling pressures
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DOI：
10.1016/j.ejheart.2008.03.005
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发表时间：
2008-05-01
影响因子：
18.2
通讯作者：
Waldenstroem, Anders
中科院分区：
文献类型：
--
作者：
Lindqvist, Per;Wikstroem, Gerhard;Waldenstroem, Anders
背景与目的：传递速度与心肌早期舒张速度之比（E/Em）可用于估计左室充盈压力（LVFP）。此外，E和Em发作的时间差也与LVFP相关。本研究的目的是评估这两个指标中哪一个是在异质患者组中同时进行有创手术时LVFP的最佳标记。方法与结果：对32例患者进行研究。采用脉冲组织多普勒超声心动图测量左室四节段的等容松弛时间（IVRTm）和Em。采用脉冲多普勒超声心动图测量E和IVRT。然后计算E/Em和IVRT-IVRTm （TIVRT-IVRTm）。在侧面，发现TIVRT-IVRTm与PCWP高度相关(r=-0.80, p
Background and aims: The ratio of the transmittal and myocardial early diastolic velocities (E/Em) can be used to estimate LV filling pressures (LVFP). Additionally, the time difference between the onset of E and Em also correlates to LVFP. The aim of this study was to evaluate which of these two indices is the best marker of LVFP in a heterogeneous group of patients during a simultaneous invasive procedure.Methods and results: Thirty two patients were studied. Em and the isovolumic relaxation time (IVRTm) at four segments of the LV were measured using pulsed tissue Doppler echocardiography. Pulsed Doppler echocardiography was used to measure E and IVRT. E/Em and IVRT-IVRTm (TIVRT-IVRTm) were then calculated. Highly significant correlations were found between TIVRT-IVRTm and PCWP at the lateral (r=-0.80, p