Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021.
Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021.
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DOI：
10.21037/jtd-21-1142
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发表时间：
2021-11
影响因子：
2.5
通讯作者：
Zhang L
中科院分区：
文献类型：
--
作者：
Wang C;Cheng L;Li H;Liu Z;Lou H;Shi J;Sun Y;Wang D;Yang Q;Yu H;Zhao C;Zhu D;Cheng F;Li Y;Liao B;Lu M;Meng C;Shen S;Sun Y;Zheng R;Zhang L
糖皮质激素治疗慢性鼻窦炎（CRS）是有效的，但对潜在的副作用的关注仍然存在，特别是对于长期全身使用糖皮质激素。累积的证据表明，经鼻雾化吸入可能是平衡疗效和安全性的合理解决方案。然而，没有共识或指南已制定使用类固醇经鼻雾化治疗CRS。通过文献回顾和中国变态反应学会耳鼻咽喉眼科学组专家交流，达成共识。本文件涵盖了类固醇经鼻雾化的发展、设备、药理机制、循证有效性和安全性，以及在冠状病毒病（COVID-19）大流行期间应用的特殊关注。专家共识阐明了类固醇经鼻雾化在围手术期和术后治疗CRS和常见合并症中的应用。
Corticosteroids are efficacious in treating chronic rhinosinusitis (CRS), but concerns on the potential side effects remain, especially for long-term usage of systemic corticosteroids. Accumulated evidence shows that transnasal nebulization may be a reasonable solution in balancing both efficacy and safety. However, no consensus or guideline has been formulated on the use of steroid transnasal nebulization in treating CRS. The consensus is achieved through literature review and exchange of Chinese experts in Group of Otorhinolaryngology and Ophthalmology, Chinese Society of Allergy (CSA). This document covers the development, equipment, pharmacological mechanism, and evidence-based efficacy and safety, as well as the special concern of the application of steroid transnasal nebulization during the coronavirus disease (COVID-19) pandemic. The expert consensus clarifies the application of steroid transnasal nebulization in treating CRS and common comorbidities during the perioperative and postoperative periods.
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DOI：
10.1016/s2213-2600(21)00013-8
发表时间：
2021-07
期刊：
The Lancet. Respiratory medicine
影响因子：
--
作者：
Bloom CI;Drake TM;Docherty AB;Lipworth BJ;Johnston SL;Nguyen-Van-Tam JS;Carson G;Dunning J;Harrison EM;Baillie JK;Semple MG;Cullinan P;Openshaw PJM;ISARIC investigators
通讯作者：
ISARIC investigators
影响因子：
3.4
作者：
Bhalla, Rajiv K.;Payton, Keith;Wright, Erin D.
通讯作者：
Wright, Erin D.
影响因子：
7.2
作者：
Fokkens, Wytske J.;Lund, Valerie J.;Zwetsloot, Casper P.
通讯作者：
Zwetsloot, Casper P.
影响因子：
3.9
作者：
Choi JC;Jung SY;Yoon UA;You SH;Kim MS;Baek MS;Jung JW;Kim WY
通讯作者：
Kim WY
影响因子：
1.4
作者：
Lee, Jungah;Kim, Yongshin;Kang, Hyerim
通讯作者：
Kang, Hyerim