Spatial Modeling of Human Risk of Exposure to Vector-Borne Pathogens Based on Epidemiological Versus Arthropod Vector Data

Spatial Modeling of Human Risk of Exposure to Vector-Borne Pathogens Based on Epidemiological Versus Arthropod Vector Data
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基于流行病学与节肢动物媒介数据的人类接触媒介传播病原体风险的空间模型

DOI:
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发表时间:
2008
影响因子:
2.1
通讯作者:
L. Eisen
L. Eisen
中科院分区:
农林科学3区
文献类型:
--
作者:
R. Eisen;L. Eisen

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摘要了解人类接触节肢动物媒介及其相关病原体的风险的空间模式对于针对有限的预防、监测和控制资源(例如,疫苗接种、药物管理或教育运动的空间定位;利用哨点监测病媒丰度;以及确定最有效使用农药的地区)。在许多情况下,通过使用地理信息系统方法,病媒传播疾病的风险可以以高预测精度建模,因为病媒和病原体储存库的丰度通常与环境因素有关。可以根据流行病学数据或病媒或受感染病媒的丰富程度,建立人类接触病媒传播病原体的空间风险模型,理想情况下,这些模型应具有较高的准确性,可用于预测高风险地区,而不会高估风险覆盖范围。我们使用五种发生在美国的细菌或病毒媒介传播的疾病,并通过跳蚤(鼠疫),蜱(莱姆病和兔热病),或蚊子(登革热和西尼罗河病毒病),以1)研究人类暴露于病媒传播病原体的空间风险通常如何呈现给公共卫生界和公众,以及2)评价将流行病学数据与节肢动物病媒或受感染病媒数据作为空间风险模型基础的效用。建议今后的病媒传播疾病风险建模方向包括:结合流行病学和病媒数据,建立县以下一级的空间风险模型,并利用模拟或分析模型评估维持地方病病原体所需的关键病媒丰度阈值。
Abstract Understanding spatial patterns of human risk of exposure to arthropod vectors and their associated pathogens is critical for targeting limited prevention, surveillance, and control resources (e.g., spatial targeting of vaccination, drug administration, or education campaigns; use of sentinel sites to monitor vector abundance; and identifying areas for most effective use of pesticides). Vector-borne disease risk can, in many cases, be modeled with high predictive accuracy by using geographic information system approaches because abundances of vectors and pathogen reservoirs often are associated with environmental factors. Spatial risk models for human exposure to vector-borne pathogens, which ideally should have high accuracy for predicting areas of elevated risk without overestimating risk coverage, can be constructed based on epidemiological data or abundance of vectors or infected vectors. We use five bacterial or viral vector-borne diseases occurring in the United States and with pathogen transmission by fleas (plague), ticks (Lyme disease and tularemia), or mosquitoes (dengue and West Nile virus disease) to 1) examine how spatial risk of human exposure to vector-borne pathogens typically is presented to the public health community and public and 2) evaluate the utility of basing spatial risk models on epidemiological data relative to data for arthropod vectors or infected vectors. Recommended future directions for vector-borne disease risk modeling include development of subcounty level spatial risk models combining epidemiological and vector data and the use of simulation or analytical models to assess critical vector abundance thresholds required for enzootic pathogen maintenance.
DOI: 10.1093/oxfordjournals.aje.a009145
发表时间: 1997-03-15
影响因子: 5
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DOI: 10.1093/jmedent/34.2.179
发表时间: 1997
影响因子: 2.1
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影响因子: 2.1
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DOI: --
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影响因子: --
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DOI: 10.1093/jmedent/32.3.267
发表时间: 1995
影响因子: 2.1
作者:
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