Structure-activity relationships among desazadesferrithiocin analogues.

Structure-activity relationships among desazadesferrithiocin analogues.
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DOI:
10.1007/978-1-4615-0593-8_9
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发表时间:
2002
影响因子:
--
通讯作者:
R. Bergeron;J. Wiegand;J. McManis;W. Weimar;Guangfei Huang
R. Bergeron;J. Wiegand;J. McManis;W. Weimar;Guangfei Huang
中科院分区:
医学4区
文献类型:
--
作者:
R. Bergeron;J. Wiegand;J. McManis;W. Weimar;Guangfei Huang

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Iron, a transition metal, represents 5% of the earth’s crust. It exists in a variety of oxidation states ranging from the zero-valent metal itself to Fe(VI), occurring in such diverse forms as iron disulfide (FeS2, “fool’s gold”), iron oxides, including magnetite (Fe304), and hemoglobin. However, the Fe(II) and Fe(III) oxidation states (Equation 1) are of the most relevance in the present discussion.