Isometric training of rats — Effects upon fast and slow muscle and modification by an anabolic hormone (Nandrolone Decanoate)
Isometric training of rats — Effects upon fast and slow muscle and modification by an anabolic hormone (Nandrolone Decanoate)
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大鼠的等长训练——对快肌和慢肌的影响以及合成代谢激素（癸酸诺龙）的改变
DOI：
10.1007/bf00587057
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发表时间：
1973
期刊：
影响因子：
--
通讯作者：
D. Pette
中科院分区：
文献类型：
--
作者：
G. Exner;H. Staudte;D. Pette
以雌性大鼠的快直肌和慢比目鱼肌为实验对象，研究了等长运动的某些效应。等长抽搐收缩时间，快肌缩短20%，慢肌延长20%。最大强直张力增加了20%，在快肌。两种肌肉供能代谢酶活性变化规律不同。不同的反应可以解释为不同的地形和纤维成分的差异。股直肌肌酸激酶、糖原磷酸化酶和磷酸丙糖脱氢酶均升高。相同的酶被发现在比目鱼肌略有下降。用癸酸诺龙处理动物导致训练动物的更高表现。在股直肌肌肉激素单独治疗引起类似的增加糖原分解和糖酵解酶的训练。此外，糖原合成酶的增加被激素诱导。这些变化不能通过额外的培训来增加。在比目鱼肌中，单独的肌肉激素治疗导致肌肉力量下降。激素处理的运动动物的等长收缩时间的延长没有发现。
Some effects of isometric exercise were studied in fast rectus femoris muscle and slow soleus muscle of the female rat. Isometric twitch contraction time shortened by 20% in fast and prolonged by 20% in slow muscle. Maximum tetanic tension increased by 20% in the fast muscle. Changes in the enzyme activity pattern of energy supplying metabolism differed in the two muscles. The different responses may be explained by different topography and differences in fibre composition. There was an increase in creatine kinase, glycogen phosphorylase and triosephosphate dehydrogenase in rectus femoris muscle. The same enzymes were found to decrease slightly in soleus muscle. Treatment of the animals with Nandrolone Decanoate caused a higher performance of the trained animals. In the rectus femoris muscle hormone treatment alone caused similar increases in glycogenolytic and glycolytic enzymes as did training. Additionally, an increase of glycogen synthetase was induced by the hormone. These changes could not be increased by additional training. In soleus muscle hormone treatment alone caused a decrease in muscle strength. In hormone treated exercising animals the prolongation of isometric twitch contraction time was not found.