Leisure-time physical activity and risk of disability incidence: A 12-year prospective cohort study among young elderly of the same age at baseline.

Leisure-time physical activity and risk of disability incidence: A 12-year prospective cohort study among young elderly of the same age at baseline.
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DOI:
10.1016/j.je.2016.11.004
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发表时间:
2017-11
影响因子:
4.7
通讯作者:
Tamakoshi A
Tamakoshi A
中科院分区:
医学3区
文献类型:
--
作者:
Matsunaga T;Naito M;Wakai K;Ukawa S;Zhao W;Okabayashi S;Ando M;Kawamura T;Tamakoshi A

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为了阐明体力活动在日本预防残疾中的作用,我们调查了年轻老年人休闲时间体力活动量与残疾发生率之间的关系。在1996年至2013年进行的新综合郊区资历调查(NISIN)项目中,我们跟踪了2,888名年龄为-65岁、无脑血管疾病病史的社区成年人,平均随访时间为11.6年。根据日本长期护理保险制度的分类,残疾的定义如下:1)支持或护理级别(支持级别1-2或护理级别1-5);2)护理级别2-5;3)痴呆症支持或护理级别;以及4)护理级别2-5或死亡。此外,我们还评估了各种原因造成的死亡率。在控制了社会人口、生活方式和医学因素后,报告活动水平为18.1代谢当量(MET)/周(有活动的人的中位数)或更多的男性参与者与不活动的组相比,被归类为支持或护理水平的痴呆症的风险降低了52%(危险比0.48;95%可信区间,0.25-0.94)。在女性中,没有发现休闲时间体力活动量与残疾发生率之间的显著关联。我们发现,在男性中,休闲时间体育活动量与患痴呆症的残疾风险之间存在反向的剂量-反应关系。因此,应该向年轻的老年男性推荐更高水平的体力活动,以预防痴呆症的残疾。我们研究了体力活动与残疾发生率之间的关系。我们量化了闲暇时间的体力活动量。痴呆患者的残疾风险存在剂量-反应关系。
To clarify the role of physical activity in preventing disability in Japan, we investigated the association between amount of leisure-time physical activity and incidence of disability among the young elderly. In the New Integrated Suburban Seniority Investigation (NISSIN) project conducted from 1996 to 2013, we followed 2888 community-dwelling adults aged 64–65 years with no history of cerebrovascular disease for a median follow-up of 11.6 years. Disabilities were defined as follows based on the classifications of the Japanese long-term care insurance system: 1) support or care levels (support levels 1–2 or care levels 1–5); 2) care levels 2–5; 3) support or care levels with dementia; and 4) care levels 2–5 or death. In addition, we also assessed 5) all-cause mortality. After controlling for sociodemographic, lifestyle, and medical factors, male participants reporting an activity level of 18.1 metabolic equivalent (MET)-hours/week (the median among those with activities) or more had 52% less risk of being classified as support or care levels with dementia compared with the no activity group (hazard ratio 0.48; 95% confidence interval, 0.25–0.94). No significant association was found among women between amount of leisure-time physical activity and incidence of disability. We identified an inverse dose–response relationship between the amount of leisure-time physical activity and the risk of disability with dementia in men. Therefore, a higher level of physical activity should be recommended to young elderly men to prevent disability with dementia. We examined associations between physical activity and disability incidence. We quantified amount of leisure-time physical activity. A dose–response relationship was found for the risk of disability with dementia.
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