Hip axis length changes in 10,554 males and females and the association with femoral neck fracture
Hip axis length changes in 10,554 males and females and the association with femoral neck fracture
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DOI：
10.1016/j.jocd.2008.04.005
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发表时间：
2008-07-01
影响因子：
2.5
通讯作者：
Yu, Jin-Bo
中科院分区：
文献类型：
--
作者：
Gao, Gao;Zhang, Zhen-Lin;Yu, Jin-Bo
髋轴长度（HAL）已被提出作为白人女性髋部骨折风险的独立预测因子。有的然而.关于其在中国的预测风险的数据很少。本研究旨在探讨中国健康人群HAL的变化及其与股骨颈骨折的关系。研究人群包括10，554名健康中国人（8665名女性，1859名男性），年龄20-97岁，居住在上海。病例为106例患者，其中女性82例。男性24例，年龄52岁以上，股骨颈骨折。对照组为106名年龄匹配的健康人。采用双能X线骨密度仪测量股骨近端和HAL各部位的骨密度。HAL与身高、体重呈显著正相关。经过身高和体重的调整。50岁及以上母畜的HAL随年龄的增加而增加，而各年龄组母畜之间的HAL无差异。在所有年龄组中，男性的HAL均长于女性。女性骨密度峰值出现在30-14岁，男性骨密度峰值出现在20-24岁，此后骨密度逐渐下降，女性骨密度峰值出现在50岁以上。骨折组和对照组的HAL相似，而股骨近端BMD值显著低于对照组。没有证据表明股骨颈骨折受试者的HAL较长。由于回顾性研究的局限性和骨折样本相对较小，需要前瞻性研究来确定结论。
Hip axis leangth (HAL) has been proposed as an independent predictor of hip fracture risk in Caucasian females. There are. however. few data concerning its predictive risk in Chinese. The aim of this study was to investigate the changes of HAL in healthy Chinese population and the relationship between HAL and femoral neck fracture. The Study population included 10,554 healthy Chinese people (8665 females, 1859 males) aged 20-97 yrs living in Shanghai. Cases were 106 patients (82 females. 24 males) aged 52 yrs old and over with femoral neck fracture. Controls were 106 age-matched healthy persons. All Subjects were measured bone mineral density (BMD) Lit any site of proximal femur and HAL using dual-energy X-ray absorptiometry. HAL had significantly positive correlations with height and weight. After the adjustment of height and weight. HAL increased with doe at 50 yrs of age and over ill females, and no difference was found among the age groups ill males. Males had longer HAL than females in all age groups. The peak BMD appeared in 30-14 yrs for females and 20-24 yrs for males and decreased thereafter, especially for females at 50 yrs old and over. HAL was similar ill both fracture and control groups, whereas the BMD values Lit proximal femur were significantly lower ill fracture group than in controls. There was no evidence that Subjects with femoral neck fracture had longer HAL. Because of the limitations of retrospective study and relatively Small fracture sample, prospective studies are required to determine the conclusions.