Management of sporadic desmoid-type fibromatosis: A European consensus approach based on patients' and professionals' expertise - A Sarcoma Patients EuroNet and European Organisation for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma Group initiative
Management of sporadic desmoid-type fibromatosis: A European consensus approach based on patients' and professionals' expertise - A Sarcoma Patients EuroNet and European Organisation for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma Group initiative
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DOI：
10.1016/j.ejca.2014.11.005
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发表时间：
2015-01-01
影响因子：
8.4
通讯作者：
Gronchi, A.
中科院分区：
文献类型：
--
作者：
Kasper, B.;Baumgarten, C.;Gronchi, A.
硬纤维瘤型纤维瘤病 (DF) 是一种罕见的单克隆成纤维细胞增殖，其特征是临床病程多变且常常不可预测。它可能影响身体的几乎所有部位，包括四肢、躯干和腹部。考虑到不同的临床表现、解剖位置和生物学行为，需要个体化的治疗方法。迄今为止，还没有治疗这种肿瘤的既定或基于证据的方法。因此，我们基于欧洲癌症研究与治疗组织 (EORTC) 软组织和骨肉瘤组 (STBSG) 的肉瘤专家与来自肉瘤患者 EuroNet (SPAEN) 的患者倡导者的圆桌会议提出了共识治疗算法。会议的目的是有史以来第一次根据专业人员和患者的专业知识制定共识方法。作为基本先决条件，所有患者都应在具有该疾病特定专业知识的中心或专业网络的多学科环境中进行讨论。 (C) 2014 Elsevier Ltd. 保留所有权利。
Desmoid-type fibromatosis (DF) is a rare monoclonal, fibroblastic proliferation characterised by a variable and often unpredictable clinical course. It may affect nearly all parts of the body including extremities, trunk and abdomen. Considering the variable clinical presentations, anatomic locations and biological behaviours, an individualised treatment approach is required. No established or evidence-based approach for the treatment of this neoplasm is available as of today. Therefore, we propose a consensus treatment algorithm based on a round table meeting bringing together sarcoma experts from the European Organisation for Research and Treatment of Cancer (EORTC) Soft Tissue and Bone Sarcoma Group (STBSG) with patient advocates from Sarcoma Patients EuroNet (SPAEN). The aim of the meeting was to develop - for the first time ever - a consensus approach based on professionals' AND patients' expertise. As a fundamental prerequisite, all patients should be discussed in a multidisciplinary setting in centres or professional networks with a specific expertise in the disease. (C) 2014 Elsevier Ltd. All rights reserved.