Activation of cell-penetrating peptides by disulfide bridge formation of truncated precursors
Activation of cell-penetrating peptides by disulfide bridge formation of truncated precursors
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DOI：
10.1039/c3cc46826g
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发表时间：
2014-01-01
影响因子：
4.9
通讯作者：
Lowik, Dennis W. P. M.
中科院分区：
文献类型：
--
作者：
Bode, Saskia A.;Wallbrecher, Rike;Lowik, Dennis W. P. M.
一个小的图书馆的寡精氨酸肽配备了末端半胱氨酸的研究方面，他们的细胞穿透性能。这些肽本身是无活性的，但在通过二硫键形成延伸其序列后获得进入细胞的能力。
A small library of oligoarginine peptides equipped with terminal cysteines was studied with respect to their cell-penetrating properties. The peptides themselves were inactive but gained the ability to enter cells upon extension of their sequence through disulfide bridge formation.