CUTANEOUS PHOTOTOXIC OCCURRENCES IN PATIENTS RECEIVING PHOTOFRIN
CUTANEOUS PHOTOTOXIC OCCURRENCES IN PATIENTS RECEIVING PHOTOFRIN
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DOI：
10.1002/lsm.1900100514
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发表时间：
1990-01-01
影响因子：
2.4
通讯作者：
MANG, TS
中科院分区：
文献类型：
--
作者：
DOUGHERTY, TJ;COOPER, MT;MANG, TS
1986-1989 年期间，在罗斯威尔帕克癌症研究所接受光动力治疗 (PDT) 的 180 名患者（266 次注射）中，对静脉注射 Photofrin 多卟啉引起的皮肤光毒性反应的发生率进行了评估。除了在随访中询问有关光毒性反应的常见口头问题外，该组中的 42 名患者还回答了一份旨在征求特定问题答案的书面调查问卷。光敏素剂量范围为 0.5 至 2.0 mg/kg。总体而言，20-40% 的患者报告了某种类型的光毒性反应。
Incidence of cutaneous phototoxic reactions induced by intravenous injection of Photofrin polyporyphyrin was assessed in a series of 180 patients (266 injection) undergoing photodynamic therapy (PDT) at Roswell Park Cancer Institute during the period 1986-1989. In addition to the usual verbal questions regarding phototoxic reactions solicited at follow-up, forty-two patients in this group also responded to a written questionnaire designed to solicit answers to specific questions. photofrin doses ranged from 0.5 to 2.0 mg/kg. Overall, 20-40% of patients reported some type of phototoxic response.