Newly Reported Lupus and Rheumatoid Arthritis in Relation to Deployment Within Proximity to a Documented Open-Air Burn Pit in Iraq
Newly Reported Lupus and Rheumatoid Arthritis in Relation to Deployment Within Proximity to a Documented Open-Air Burn Pit in Iraq
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DOI：
10.1097/jom.0b013e3182529799
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发表时间：
2012-06-01
影响因子：
3.2
通讯作者：
Smith, Tyler C.
中科院分区：
文献类型：
--
作者：
Jones, Kelly A.;Smith, Besa;Smith, Tyler C.
目的：评估已部署支持伊拉克和阿富汗行动的千年队列参与者中可能接触记录在案的露天烧伤坑的烟雾与新报告的狼疮和类风湿性关节炎之间的关系。方法：对完成 2004-2006 年和 2007-2008 年调查问卷的部署人员自我报告的狼疮和类风湿关节炎进行前瞻性评估。结果：排除后，部署了超过 18,000 名参与者，其中超过 3000 名参与者部署在记录的烧坑半径 3 英里内。调整后，烧伤坑 3 英里范围内的距离通常与类风湿性关节炎或狼疮没有显着相关性；然而，有一个位置与狼疮相关，尽管很少有病例出现在该位置（n = 2）。结论：结果表明，在三营综合分析中，可能接触记录在案的烧伤坑的部署人员患狼疮或类风湿性关节炎的风险并不升高。
Objective: To assess the relationship between possible exposure to smoke from documented open-air burn pits and newly reported lupus and rheumatoid arthritis among Millennium Cohort participants who have deployed in support of operations in Iraq and Afghanistan. Methods: Prospectively assessed self-reported lupus and rheumatoid arthritis among deployers who completed both 2004-2006 and 2007-2008 questionnaires. Results: After exclusions, more than 18,000 participants were deployed, including more than 3000 participants deployed within a 3-mile radius of a documented burn pit. After adjustment, proximity within 3 miles of a burn pit was not significantly associated with rheumatoid arthritis or lupus in general; however, one location was associated with lupus, although few cases were at this site (n = 2). Conclusions: Results indicate deployers potentially exposed to documented burn pits in the combined three-camp analysis were not at an elevated risk of lupus or rheumatoid arthritis.