VOLTAGE-SENSITIVE DYES REVEAL A MODULAR ORGANIZATION IN MONKEY STRIATE CORTEX
VOLTAGE-SENSITIVE DYES REVEAL A MODULAR ORGANIZATION IN MONKEY STRIATE CORTEX
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DOI：
10.1038/321579a0
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发表时间：
1986-06-05
期刊：
影响因子：
64.8
通讯作者：
SALAMA, G
中科院分区：
文献类型：
--
作者：
BLASDEL, GG;SALAMA, G
电压敏感的染料允许通过非侵入性光学技术研究神经元活性。它们提供了一种有吸引力的方法来研究条纹皮层，其中重要的响应特性在两个维度上组织起来。在本研究中，使用染料蛋白丙氨酸恶唑酮以及当前的图像处理技术从同一皮层中反复从同一皮层中重复获得眼部优势和方向选择性的模式。观察到的模式符合猴子层皮层的大多数既定特征，并提出了一个新的皮质组织。一个模块化的结构，似乎将方向选择性的组织与眼部优势联系起来。
Voltage-sensitive dyes allow neuronal activity to be studied by non-invasive optical techniques. They provide an attractive means of investigating striate cortex, where important response properties are organized in two dimensions. In the present study, patterns of ocular dominance and orientation selectivity were obtained repeatedly from the same patch of cortex using the dye merocyanine oxazolone, together with current image-processing techniques. The patterns observed agree with most established features of monkey striate cortex and suggest a new unit of cortical organization; one that is modular in structure and which appears to link the organization of orientation selectivity with that of ocular dominance.