Construct validity of the Patient-Reported Outcomes Measurement Information System gastrointestinal symptom scales in systemic sclerosis.
Construct validity of the Patient-Reported Outcomes Measurement Information System gastrointestinal symptom scales in systemic sclerosis.
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DOI：
10.1002/acr.22337
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发表时间：
2014-11
影响因子：
4.7
通讯作者：
Khanna, Dinesh
中科院分区：
文献类型：
--
作者：
Nagaraja, Vivek;Hays, Ron D.;Khanna, Puja P.;Spiegel, Brennan M. R.;Chang, Lin;Melmed, Gil Y.;Bolus, Roger;Khanna, Dinesh
Gastrointestinal (GI) involvement is common in patients with systemic sclerosis (SSc). The Patient-Reported Outcomes Measurement Information System (PROMIS®) GI Symptom item bank captures upper and lower GI symptoms (reflux, disrupted swallowing, nausea/vomiting, belly pain, gas /bloating /flatulence, diarrhea, constipation, and fecal incontinence). The objective of this study was to evaluate the construct validity of the PROMIS-GI bank in SSc. 167 patients with SSc were administered the PROMIS GI bank and the UCLA Scleroderma Clinical Trials Consortium Gastrointestinal Scale (GIT 2.0) instrument. GIT 2.0 is a multi-item instrument that measures SSc-associated GI symptoms. Product-moment correlations and a multitrait-multimethod analysis of the PROMIS GI scales with the GIT 2.0 symptom scales were used to evaluate convergent and discriminant validity. Patients with SSc GI involvement had PROMIS GI scale scores 0.2–0.7 SD worse than US population. Correlations among scales measuring the same domains for the PROMIS GI and GIT 2.0 measures were large, ranging from 0.61 to 0.87 (average r = 0.77). The average correlation between different symptom scales was 0.22, supporting discriminant validity. This study provides support for the construct validity of the PROMIS GI scales in SSc. Future research is needed to assess the responsiveness to change of these scales in patients with SSc.
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影响因子：
3.4
作者：
Spiegel BM
通讯作者：
Spiegel BM
影响因子：
7.2
作者：
Rose, M.;Bjomer, J. B.;Ware, J. E.
通讯作者：
Ware, J. E.
影响因子：
9.8
作者：
Spiegel, Brennan M. R.;Khanna, Dinesh;Chang, Lin
通讯作者：
Chang, Lin
影响因子：
22.4
作者：
CAMPBELL, DT;FISKE, DW
通讯作者：
FISKE, DW
影响因子：
4.5
作者：
Khanna, Dinesh;Maranian, Paul;Hays, Ron D.
通讯作者：
Hays, Ron D.