A MULTISTATE OUTBREAK OF NORWALK VIRUS GASTROENTERITIS ASSOCIATED WITH CONSUMPTION OF COMMERCIAL ICE
A MULTISTATE OUTBREAK OF NORWALK VIRUS GASTROENTERITIS ASSOCIATED WITH CONSUMPTION OF COMMERCIAL ICE
复制标题
DOI：
10.1093/infdis/164.5.860
复制
发表时间：
1991-11-01
影响因子：
6.4
通讯作者：
GLASS, RI
中科院分区：
文献类型：
--
作者：
CANNON, RO;POLINER, JR;GLASS, RI
1987年9月19日至27日，在参加过特拉华州威尔明顿博物馆募捐活动和费城大学校际足球赛的人群中，发生了一系列胃肠疾病的爆发。 对参加这些活动的四个群体进行的调查显示，31%（191/614）的人生病。 总的来说，那些吃冰的人呕吐或腹泻的可能性是那些不吃冰的人的12倍（发作率，55%对4%，P <0.001）。 9月8日，宾夕法尼亚州东南部的一家制造商在一场暴雨后被附近的一条小溪淹没，导致威尔斯的水井受到污染。 在19名感染者中，有13人（68%）在接触后一周内检测到诺瓦克病毒抗体滴度至少增加了四倍。 这份报告是第一份记录受污染的商业冰块与诺瓦克胃肠炎之间联系的报告，应该会促使政府重新评估对冰块生产和销售的监管。
Between 19 and 27 September 1987, a cluster of outbreaks of gastrointestinal illness occurred among persons who had attended a museum fund-raiser in Wilmington, Delaware and an intercollegiate football game in Philadelphia. A survey of four groups attending these events showed that 31% (191/614) became ill. Altogether, those who consumed ice were 12 times more likely to experience either vomiting or diarrhea than those who did not (attack rate, 55% vs. 4%, P < .001). Ice consumed at the events was traced to a manufacturer in southeastern Pennsylvania whose wells had been contaminated when flooded by a nearby creek after a torrential rainfall on 8 September. Of 19 affected persons tested within 1 week of exposure, 13 (68%) had at least a fourfold rise in antibody titer to the Norwalk virus. This report, the first to document an association of contaminated commercial ice with Norwalk gastroenteritis should prompt reassessment of government regulation of the production and distribution of ice.