Histochemical investigations on succinic dehydrogenase in the central nervous system. II. Atlas of the medulla oblongata of the guinea pig.
Histochemical investigations on succinic dehydrogenase in the central nervous system. II. Atlas of the medulla oblongata of the guinea pig.
复制标题
中枢神经系统琥珀酸脱氢酶的组织化学研究。
DOI：
10.1111/j.1471-4159.1959.tb13180.x
复制
发表时间：
1959
影响因子：
4.7
通讯作者：
Friede Rl
中科院分区：
文献类型：
--
作者：
Friede Rl
最近，SIUMIZU 和 MORIKAWA (1957) 的一项基础研究报告了啮齿类动物脑组织中琥珀酸脱氢酶活性 (SDA) 的分布。在本报告中，详细描述了豚鼠延髓中的核模式，其定义是通过神经组织内琥珀酸脱氢酶的演示来定义的。结果是通过利用改进的切割技术（FRIEDE，1958）获得的，该技术最大限度地减少了对组织的创伤影响，并允许在精细和精致的结构（特别是神经纤维）中展示 SDA。在某些情况下，该技术证明亚核之间微小差异的能力绝对超过了通常的细胞结构技术所获得的结果。进一步的观察将表明，使用 SDA 技术，即使皮质区域之间的差异也非常明显。希望本文中呈现的延髓切片的显微照片以及对细胞核的详细描述能够提供正常活动的图谱，作为神经解剖学、神经生理学和实验神经病理学的基础。重要性应该归因于这样一个事实，即所采用的组织化学技术提供了一种展示神经纤维的方法，神经纤维是神经系统的一部分，但很难获得传统的神经组织学技术。该图谱的命名和排列与MEE~~EN和OLSZEWSKI (1949)的兔子菱形脑的细胞结构图谱相对应。因此，本报告的板可以很容易地与这些作者的细胞结构图谱的板进行比较。本文不讨论豚鼠延髓的细胞结构，因为它与兔子的细胞结构非常相似。
THE distribution of succinic dehydrogenase activity (SDA) in brain tissue of rodents has been reported recently in a fundamental study by SIUMIZU and MORIKAWA (1957). In the present report a detailed description of the nuclear pattern in the medulla oblongata of the guinea pig is presented as defined by the demonstration of succinic dehydrogenase within nervous tissue. The results were obtained by utilizing an improved cutting technique (FRIEDE, 1958) which minimizes traumatic effects to the tissue and allows the demonstration of SDA in fine and delicate structures, in particular, the neuropil. In some instances, the capability of the technique to demonstrate the minute differences between subnuclei definitely exceeds the results obtained by the usual cytoarchitectonic techniques. Further observations will show that even differences between cortical areas are quite clear with the SDA technique. It is hoped that the microphotographs of sections of the medulla oblongata presented in this paper together with a detailed description of the nuclei will provide a mapping of normal activity, useful as a base in neuroanatomy, neurophysiology and experimental neuropathology. Importance should be attributed to the fact that the histochemical technique employed offers a method for demonstrating the neuropil, a part of the nervous system which offers very poor access to the conventional techniques of neurohistology.The nomenclature and arrangement of this atlas corresponds to that of the cytoarchitectonic atlas of the rhombencephalon of the rabbit by MEE~~ EN and OLSZEWSKI (1949). Thus, the plates of this report may readily be compared with the plates of the cytoarchitectonic atlas of these authors. The cytoarchitecture of the medulla oblongata of the guinea pig is not dealt with in the present article, since it is very similar to that of the rabbit.