Friction coefficient and wettability of oral mucosal tissue: Changes induced by a salivary layer
Friction coefficient and wettability of oral mucosal tissue: Changes induced by a salivary layer
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DOI：
10.1016/j.colsurfa.2005.10.033
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发表时间：
2006-03-15
影响因子：
5.2
通讯作者：
Humbert, P
中科院分区：
文献类型：
--
作者：
Ranc, H;Elkhyat, A;Humbert, P
体外测定舌粘膜在去除唾液层时的摩擦系数、润湿性和表面自由能，以及唾液涂层对这些特性的影响。由于仔猪舌头与人类舌头有相似之处，且有大量标本可用，因此被用作实验的支撑物。收集完整的刺激唾液(新鲜的人类唾液)，并以此方式使用。在有机唾液层形成之前和之后，使用为表征人类皮肤特性而开发的设备测试口腔粘膜组织的摩擦和润湿特性。通过提前测量接触角来确定舌面的润湿性。以蒸馏水、二碘甲烷和乙二醇作探针液。在实验条件下，舌面呈疏水性，呈弱极性。当被唾液层覆盖时，舌头的表面明显变得更亲水。唾液涂层增加了舌背表面的总表面自由能，同时赋予了一种更基本的特征。此外，唾液层的存在使动态摩擦系数降低了1.6倍，这是唾液的润滑剂功能的基础。总而言之，舌面的摩擦和润湿特性提供了有价值的洞察舌面如何作为涂层的函数与其他表面相互作用。(C)2005 Elsevier B.V.保留所有权利。
The friction coefficient, the wettability and the surface free energy of lingual mucosa while deprived of its natural removable salivary layer were evaluated ex vivo and the influence of a salivary coating on these characteristics assessed. Piglet tongue was used as support for the experiments due to its known similarities with human tongue and the availability of a large number of specimens. Whole stimulated saliva (fresh human saliva) was collected and used as Such. The friction and wettability properties of the oral mucosal tissue were tested before and after organic salivary layer formation using devices developed to characterise human skin properties. Tongue surface wettability was determined by advancing contact angle measurements. Distilled water, diiodomethane and ethylene glycol were used as probe liquids. Under experimental conditions, the tongue Surface has a hydrophobic tendency and is weakly polar. When coated with a salivary layer, the surface of the tongue becomes significantly more hydrophilic. Salivary coatings increase the total surface free energy of the dorsal surface of the tongue and at the same time impart a more basic character. Moreover, the presence of salivary layers reduces the dynamic coefficient of friction by a factor of 1.6, underlying the lubricant function of saliva. In conclusion, friction and wetting properties of tongue surface provide valuable insight into how the tongue interacts with other surfaces as a function of the coating. (c) 2005 Elsevier B.V. All rights reserved.