Neural correlates of social exclusion during adolescence: understanding the distress of peer rejection
Neural correlates of social exclusion during adolescence: understanding the distress of peer rejection
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DOI：
10.1093/scan/nsp007
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发表时间：
2009-06-01
影响因子：
4.2
通讯作者：
Dapretto, Mirella
中科院分区：
文献类型：
--
作者：
Masten, Carrie L.;Eisenberger, Naomi I.;Dapretto, Mirella
发展研究已经证明了青少年时期同伴拒绝的有害影响;然而，负责这种显着性的神经机制仍然未被探索。在这项研究中，23名青少年被排除在一个抛球游戏中，在功能磁共振成像扫描过程中，他们认为自己是在和另外两名青少年一起玩;实际上，参与者玩的是一个预设的计算机程序。之后，参与者报告了他们的排斥相关的痛苦和拒绝敏感性，父母报告了参与者的人际交往能力。与成年人的研究结果相似，在社会排斥期间，青少年表现出与自我报告的痛苦呈正相关的岛屿活动，以及与自我报告的痛苦呈负相关的右腹外侧前额叶活动。青少年特有的研究结果表明，前扣带皮层（subACC）的活动与更大的痛苦有关，腹侧纹状体的活动与更少的痛苦有关，似乎在调节subACC和其他涉及情绪困扰的区域的活动中发挥作用。最后，具有较高的拒绝敏感性和人际交往能力分数的青少年表现出更大的神经证据的情绪困扰，和青少年具有较高的人际交往能力分数也表现出更大的神经证据的监管，也许表明，青少年谁是警惕的同伴接受可能是最敏感的拒绝的经验。
Developmental research has demonstrated the harmful effects of peer rejection during adolescence; however, the neural mechanisms responsible for this salience remain unexplored. In this study, 23 adolescents were excluded during a ball-tossing game in which they believed they were playing with two other adolescents during an fMRI scan; in reality, participants played with a preset computer program. Afterwards, participants reported their exclusion-related distress and rejection sensitivity, and parents reported participants' interpersonal competence. Similar to findings in adults, during social exclusion adolescents displayed insular activity that was positively related to self-reported distress, and right ventrolateral prefrontal activity that was negatively related to self-reported distress. Findings unique to adolescents indicated that activity in the subgenual anterior cingulate cortex (subACC) related to greater distress, and that activity in the ventral striatum related to less distress and appeared to play a role in regulating activity in the subACC and other regions involved in emotional distress. Finally, adolescents with higher rejection sensitivity and interpersonal competence scores displayed greater neural evidence of emotional distress, and adolescents with higher interpersonal competence scores also displayed greater neural evidence of regulation, perhaps suggesting that adolescents who are vigilant regarding peer acceptance may be most sensitive to rejection experiences.