Anterior chamber depth in elderly Chinese
Anterior chamber depth in elderly Chinese
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DOI：
10.1016/j.ophtha.2007.12.003
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发表时间：
2008-08-01
期刊：
影响因子：
13.7
通讯作者：
Foster, Paul J.
中科院分区：
文献类型：
--
作者：
He, Mingguang;Huang, Wenyong;Foster, Paul J.
目的：评价中国南方城市地区老年人前房深度（ACD）及其随年龄、性别和角宽度的变化。设计：横断面研究。研究对象：采用整群随机抽样方法，选取广州市荔湾区50岁及以上的成年人。方法：在ACD测量前进行角镜检查，根据Shaffer系统估计几何角度宽度。采用光学测厚法测量ACD。通过角膜前上皮与前晶状体囊之间的距离减去角膜中央厚度来计算真实ACD。给出了右眼的数据。主要观察指标：前房深度和角镜检查。结果：在1405名参与者中，有1248只右眼的数据可供分析。男性和女性的平均ACD值分别为2.59 mm（95%置信区间[CI]， 2.56-2.62； 25 -75百分位数，2.37-2.82）和2.42 mm（95%置信区间，2.39-2.44；25 -75百分位数，2.21-2.63）。平均ACD每十年下降0.09毫米（95% CI, -0.011至-0.008）（按性别调整），女性比男性浅0.18毫米（95% CI, -0.213至-0.141）（按年龄调整）。ACD与角宽度单调相关，从Shaffer 4级的2.73 mm（标准差[SD]， 0.26）下降到Shaffer 0级的1.94 mm （SD, 0.27）。ACD与屈光不正也有关系；平均球当量每屈光度降低0.030 mm ACD。结论：本研究证实ACD与年龄、女性性别和球面屈光不正呈负相关。ACDs较浅的眼睛角度较窄。
Purpose: To assess the anterior chamber depth (ACD) and its variation with age, gender, and angle width in elderly Chinese in an urban area of southern China.Design: Cross-sectional study.Participants: Adults 50 and older were identified using cluster random sampling in Liwan District, Guangzhou.Methods: Gonioscopy was performed before ACD measurements to estimate the geometric angle width according to the Shaffer system. ACD was measured using optical pachymetry. True ACD was calculated by subtracting central corneal thickness from the distance between the anterior corneal epithelium and the anterior lens capsule. Data were presented for the right phakic eyes.Main Outcome Measures: Anterior chamber depth and gonioscopy.Results: Among 1405 participants in the study, data from 1248 right eyes were available for analysis. The mean ACD values for men and women were 2.59 mm (95% confidence interval [CI], 2.56-2.62; 25th-75th percentile, 2.37-2.82) and 2.42 mm (95% Cl, 2.39-2.44; 25th-75th percentile, 2.21-2.63). Mean ACD declined by 0.09 mm (95% CI, -0.011 to -0.008) per decade (adjusted for gender) and was 0.18 mm (95% CI, -0.213 to -0.141) shallower in women than men (adjusted for age). The ACD was found to be monotonically associated with gonioscopic angle width, decreasing from 2.73 mm (standard deviation [SD], 0.26) in Shaffer grade 4 to 1.94 mm (SD, 0.27) in Shaffer grade 0. There was also a relationship between ACD and refractive error; mean spherical equivalent decreased by 0.030 mm ACD per diopter.Conclusions: This study confirms an inverse association between ACD and age, female gender, and spherical refractive error. Eyes with shallower ACDs had narrower angles.