SARS-CoV-2 Is Present in Peritoneal Fluid in COVID-19 Patients
SARS-CoV-2 Is Present in Peritoneal Fluid in COVID-19 Patients
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DOI：
10.1097/sla.0000000000004030
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发表时间：
2020-09-01
影响因子：
9
通讯作者：
Chiarugi, Massimo
中科院分区：
文献类型：
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作者：
Coccolini, Federico;Tartaglia, Dario;Chiarugi, Massimo
背景：SARS-CoV-2的排泄机制目前尚不清楚。在疾病的不同阶段，没有关于不同身体隔室和体液中病毒载量的特定数据。材料和方法：采用针对3个SARS-CoV-e基因的特异性实时逆转录-聚合酶链式反应检测病毒的存在。结果：SARS-CoV-2在腹腔液中的浓度高于呼吸道。结论：腹腔液中检出SARS-CoV-2尚未见报道。这篇文章是描述新冠肺炎患者在紧急外科手术期间腹腔液中存在病毒的第一个阳性结果。因此，这篇文章对提高外科医生的意识和保护水平提出了警告，特别是在紧急手术环境中。
Background: The excretion pathomechanisms of SARS-CoV-2 are actually unknown. No certain data exist about viral load in the different body compartments and fluids during the different disease phases. Material and Methods: Specific real-time reverse transcriptase-polymerase chain reaction targeting 3 SARS-CoV-e genes were used to detect the presence of the virus. Results: SARS-CoV-2 was detected in peritoneal fluid at a higher concentration than in respiratory tract. Conclusion: Detection of SARS-CoV-2 in peritoneal fluid has never been reported. The present article represents the very first positive result describing the presence of the virus in peritoneal fluid during an emergency surgical procedure in a COVID-19 sick patient. This article thus represents a warning for increasing the level of awareness and protection for surgeon especially in emergency surgical setting.