Neural interface technology for rehabilitation: exploiting and promoting neuroplasticity.
Neural interface technology for rehabilitation: exploiting and promoting neuroplasticity.
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DOI：
10.1016/j.pmr.2009.07.003
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发表时间：
2010-02
影响因子：
1.7
通讯作者：
Weber, Douglas J
中科院分区：
文献类型：
--
作者：
Wang, Wei;Collinger, Jennifer L;Perez, Monica A;Tyler-Kabara, Elizabeth C;Cohen, Leonardo G;Birbaumer, Niels;Brose, Steven W;Schwartz, Andrew B;Boninger, Michael L;Weber, Douglas J
康复的主要目标是恢复身体，心理和社会功能，并改善患有各种运动，感觉和/或认知障碍的个人的生活质量。虽然治疗方案从药物到体育锻炼各不相同，但本文重点介绍神经接口技术，也称为神经修复术，其功能是通过与神经系统直接相互作用来实现的。Luigi Galvani在两百多年前就记录了腿部肌肉收缩可以通过电刺激股神经引起1，2。然而，直到最近几十年，神经接口技术才开始受到生物医学工程师、神经科学家和临床医生越来越多的关注，这主要是由于电子医疗设备和系统神经科学研究的巨大进步。美国食品和药物管理局（FDA）于1984年批准人工耳蜗植入治疗听力损失，并于2000年批准深部脑刺激器（DBS）治疗帕金森病。美国国立卫生研究院目前每年举办两次神经接口会议，目的是将行业合作伙伴，
The primary goal of rehabilitation is to restore physical, psychological, and social functions and improve the quality of life for individuals with various motor, sensory, and/or cognitive impairments. While treatment options vary from pharmacological agents to physical exercise, this review paper focuses on neural interface technology, also called neuroprosthetics, which functions by directly interacting with the nervous system either electrically or magnetically. Luigi Galvani documented more than two hundred years ago that leg muscle contraction can be elicited by electrical stimulation of the femoral nerve 1, 2. However, it is only in the last several decades that neural interface technology started to receive increasing attention from biomedical engineers, neuroscientists, and clinicians, largely due to great advance in electronic medical devices and system neuroscience research. The US Food and Drug Administration (FDA) approved cochlear implants for treating hearing loss in 1984 and deep brain stimulators (DBS) for treating Parkinson's disease in 2000 3. The National Institutes of Health currently holds a bi-annual Neural Interface Conference with the goal of bringing industry partners,