Identification of climate factors related to human infection with avian influenza A H7N9 and H5N1 viruses in China.
Identification of climate factors related to human infection with avian influenza A H7N9 and H5N1 viruses in China.
复制标题
中国人感染甲型H7N9和H5N1禽流感病毒相关气候因素的鉴定
DOI：
10.1038/srep18094
复制
发表时间：
2015-12-11
影响因子：
4.6
通讯作者：
Liu W
中科院分区：
文献类型：
--
作者：
Li J;Rao Y;Sun Q;Wu X;Jin J;Bi Y;Chen J;Lei F;Liu Q;Duan Z;Ma J;Gao GF;Liu D;Liu W
人类的影响表现出强烈的季节性模式。主要发生在中国的南部，中和西北，而H7N9的发生集中在东部和除了空间时期的特征外，中国南部，这两个病毒亚型的人类感染最适应性的气象条件是不同的。 ），而H5N1感染与TEM和大气压相关（PR）。 H7N9感染和（TEM 2–22°C和PRS 980-1025 kPa）的65–95％）用于H5N1感染。未来的指南何时属于风险的窗口。未来爆发。
Human influenza infections display a strongly seasonal pattern. However, whether H7N9 and H5N1 infections correlate with climate factors has not been examined. Here, we analyzed 350 cases of H7N9 infection and 47 cases of H5N1 infection. The spatial characteristics of these cases revealed that H5N1 infections mainly occurred in the South, Middle and Northwest of China, while the occurrence of H7N9 was concentrated in coastal areas of East and South of China. Aside from spatial-temporal characteristics, the most adaptive meteorological conditions for the occurrence of human infections by these two viral subtypes were different. We found that H7N9 infections correlate with climate factors, especially temperature (TEM) and relative humidity (RHU), while H5N1 infections correlate with TEM and atmospheric pressure (PRS). Hence, we propose a risky window (TEM 4–14 °C and RHU 65–95%) for H7N9 infection and (TEM 2–22 °C and PRS 980-1025 kPa) for H5N1 infection. Our results represent the first step in determining the effects of climate factors on two different virus infections in China and provide warning guidelines for the future when provinces fall into the risky windows. These findings revealed integrated predictive meteorological factors rooted in statistic data that enable the establishment of preventive actions and precautionary measures against future outbreaks.