PHYSIOLOGY OF PERIPHERAL NEURONS INNERVATING SEMICIRCULAR CANALS OF SQUIRREL MONKEY .1. RESTING DISCHARGE AND RESPONSE TO CONSTANT ANGULAR ACCELERATIONS
PHYSIOLOGY OF PERIPHERAL NEURONS INNERVATING SEMICIRCULAR CANALS OF SQUIRREL MONKEY .1. RESTING DISCHARGE AND RESPONSE TO CONSTANT ANGULAR ACCELERATIONS
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DOI：
10.1152/jn.1971.34.4.635
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发表时间：
1971-01-01
影响因子：
2.5
通讯作者：
FERNANDEZ, C
中科院分区：
文献类型：
--
作者：
GOLDBERG, JM;FERNANDEZ, C
方法45只体重从450克到950克的雄性松鼠猴(Saimiri Sciureus)提供了有用的数据。所有实验均在左侧进行。动物用戊巴比妥钠(15 mg/kg)麻醉；随后给药以维持中等水平的麻醉。体温维持在35~38℃，旋转圆形骨瓣。该皮瓣的半径为8 mm，中心位于额顶骨交界处后13 mm处，中线外侧8 mm处。通过抽吸和钝性解剖相结合的方法切除顶内沟后面的大脑皮层，显露小脑。消融范围包括左侧顶叶和颞叶的后部以及整个左侧枕叶。小脑幕被切开并反射。小脑的前外侧角--包括部分鞍状叶、小叶旁和小叶小叶--通过温和的吸引术消融。这暴露了第七和第八脑神经1.5-2.0毫米的距离，从它们出现在内耳道到脑干的边缘(图1)。可见前庭神经上支，多数情况下可见其下支。采取了两项预防措施来固定
METHODSForty-five male squirrel monkeys (Saimiri sciureus), ranging in weight from 450 to 950 g, provided useful data. All experiments were performed on the left side. The animals were anesthetized with pentobarbital sodium (15 mg/kg); subsequent doses were given to maintain a moderate level of anesthesia. Temperature was maintained at 35-38 C. A circular bone flap was turned. The radius of the flap was 8 mm; its center was located 13 mm poste-rior to the junction of the frontal and parietal bones and 8 mm lateral to the midline. The cerebellum was exposed by removing the cerebral cortex posterior to the intraparietal sulcus with a combination of aspiration and blunt dissection. The ablation included the posterior parts of the left parietal and temporal cortex as well as the whole of the left occipital lobe. The cerebellar tentorium was incised and reflected. The anterolateral angle of the cerebellum-including portions of the ansiform lobe, the paraflocculus, and the flocculus-was ablated by gentle aspiration. This exposed the seventh and eighth cranial nerves for a distance of 1.5-2.0 mm, from their emergence in the internal auditory meatus to the edge of the brain stem (Fig. 1). The supe-rior branch of the vestibular nerve and, on most occasions, its inferior branch were visible. Two precautions were taken to immobilize