Best practices for cystometric evaluation of lower urinary tract function in muriform rodents.
Best practices for cystometric evaluation of lower urinary tract function in muriform rodents.
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DOI：
10.1002/nau.24415
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发表时间：
2020-08
影响因子：
2
通讯作者：
Yoshiyama M
中科院分区：
文献类型：
--
作者：
Fraser MO;Smith PP;Sullivan MP;Bjorling DE;Campeau L;Andersson KE;Yoshiyama M
啮齿类动物膀胱术为疾病、损伤和衰老对下尿路功能的细胞和分子途径、神经过程和生物力学的影响提供了有价值的见解。本白皮书的目的是强调不同实验方法和策略的优点和缺点，并为正确解释结果提供指导。本文描述了一系列用于探索与下尿路相关的生物现象的膀胱测量测试和技术，讨论了各种实验条件的优点和缺点，并提供了实验执行和正确解释结果的实际方面的指导。啮齿类动物的膀胱测量评估包括广泛的功能测试集合，可以在各种实验条件下进行。关于选择哪种方法的决定应由要解决的具体问题决定，测试的实施应遵循标准化程序。
Rodent cystometry has provided valuable insights into the impact of disease, injury, and aging on the cellular and molecular pathways, neurologic processes, and biomechanics of lower urinary tract function. The purpose of this white paper is to highlight the benefits and shortcomings of different experimental methods and strategies, and to provide guidance on the proper interpretation of results. Literature search, selection of articles, and conclusions based on discussions among a panel of workers in the field A range of cystometric tests and techniques used to explore biological phenomena relevant to the lower urinary tract are described, the advantages and disadvantages of various experimental conditions are discussed, and guidance on the practical aspects of experimental execution and proper interpretation of results are provided. Cystometric evaluation of rodents comprises an extensive collection of functional tests that can be performed under a variety of experimental conditions. Decisions regarding which approaches to choose should be determined by the specific questions to be addressed and implementation of the test should follow standardized procedures.
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影响因子：
6.6
作者：
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通讯作者：
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作者：
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DOI：
10.1152/ajpregu.00142.2006
发表时间：
2007-04-01
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DOI：
10.1152/ajpregu.00780.2005
发表时间：
2006-07-01
影响因子：
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作者：
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